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Orthodontic diagnosis and treatment in the mixed dentition

John Fricker, Om P Kharbanda and Julia Dando

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Introduction

The primary aim of orthodontic assessment in a growing child is to differentiate between a developing normal occlusion and a potential malocclusion, including any abnormal growth of the face and function of the stomatognathic system. It is essential to have a sound understanding of facial growth and dental development, and the ability to recognize the rate and direction of facial and dental growth. Many situations of apparent malocclusion in the mixed dentition are actually manifestation of the normal process of dental and facial development. Minor incisor irregularities, spacing and ectopic eruption of teeth, which may show up during the mixed dentition, could self-correct with growth and development.

Correction of dental arch irregularities, occlusal and jaw relation abnormalities and elimination of functional interferences may be classified as preventive or interceptive. The term ‘preventive orthodontics’ implies steps undertaken for elimination of factors that may lead to malocclusion in an otherwise normally developing dentition.

‘Interceptive orthodontics’ implies that corrective measures may be necessary to intercept a potential irregularity from progressing into a more severe malocclusion. Neither the appliances used nor the treatment itself should interfere with the often rapid changes in eruption of permanent teeth and the dynamic nature of occlusal adjustment. It is important to understand that even when such procedures are carried out, a majority of these children will go on to require some further treatment in the permanent dentition.

Orthodontic assessment of a child

An orthodontic assessment in common with other specialties, must include a good history, a thorough clinical examination and any relevant investigations. The information gathered leads to a diagnosis, which in turn allows treatment planning. This topic is covered in detail in Chapter 1. Additional points relevant to aid orthodontic diagnosis, however, will now be discussed.

The child should be assessed for skeletal and dental problems and abnormalities of functions of the stomatognathic system. Clinical assessment is performed in all the three dimensions of space, i.e. vertical, anteroposterior and transverse.

Dental relationships

Dental relationships are recorded with the teeth in occlusion. It describes the anteroposterior relationship of the upper and lower molars according to Angle’s classification and the anteroposterior incisor relationship according to the British Standards Institute classification (1983). Angle’s classification of malocclusion is based on the relationship of the upper and lower first permanent molars.

Orthodontic examination

Extra-oral

The physical status of the child should be included here, and if relevant, height and weight should be recorded on a standard growth chart. It is essential to determine if the face of the child is also growing normally. The face is examined with the child sitting upright. This is important because the mandibular rest position will change, if lying back.

Evaluation of crowding

In the permanent dentition, it is easy to assess the amount of crowding by taking measurements directly from study models. Treatment will depend on the severity of the problem and may involve arch lengthening or extractions. In the mixed dentition, however, a prediction of future crowding is necessary.

Mixed dentition analysis

The purpose of a mixed dentition analysis is to determine the space available in the dental arch for the permanent successors to erupt. To complete this analysis, it is necessary to first record the arch length and the mesiodistal widths of the mandibular permanent incisors.

Crowding and space management in the mixed dentition

Space management can minimize the development of crowding in the permanent dentition. It essentially involves:

• Space maintenance following the premature loss of primary molars.

• Utilization of the leeway space by placement of holding arches.

Space maintenance

The best space maintenance treatment is the preservation of the primary molars until natural exfoliation. Although dental health education and improved caries prevention have lowered the number of children who develop malocclusion because of premature loss of primary teeth, it is still one of the most common controllable causes of malocclusion.

When a primary second molar is lost prematurely due to caries or to the ectopic eruption of the first permanent molar, the first permanent molar will drift mesially. This is most pronounced in the maxilla with a more rapid shift of the molar and causing a Class II malocclusion. The earlier the loss of the second primary molar and the less the root development of the permanent molar, the greater will be the amount of bodily mesial shift of the permanent molar.

Types of space maintainer

Regaining space

Within an arch, space may need to be regained when migration of permanent teeth has already occurred following the loss of adjacent deciduous teeth (Figure 14.7). Furthermore, space maintenance would then be needed until the permanent successor erupted. In the maxilla, this would intercept a developing Class II, dental relationship secondary to mesial migration and rotation of the first permanent molar. In the mandible, it could prevent a mild dental Class III relationship by uprighting tipped lower first permanent molars. In individuals with a developing skeletal discrepancy, the dental correction would have no effect on the underlying skeletal problem.

In general, tooth movement is slower in cases with severe horizontal growth pattern (low FMPA). Conversely, it is rapid in vertical growers, and space loss can occur very quickly. Early fitting of a space maintainer will prevent space loss. If space is to be regained, it is essential that the mechanics should not extrude the teeth at all.

Radiographs and study models are essential aids in assessing space needs. It is important to note whether teeth have moved bodily or have tipped into the space. Tipping can be easier to resolve than bodily tooth movement. Radiographic examination should also locate the permanent second molars and establish space available for distalization of the first permanent molars.

Appliances used to regain space

• Uprighting mechanics:

• Sectional fixed appliance.

• Removable appliances – Acrylic cervical occipital appliance (ACCO appliance).

An ACCO appliance (Figure 14.8) is comprised of a palatal acrylic plate with an anterior bite platform to disclude the posterior teeth, allowing the first permanent molar to move freely. Retention is obtained via Adams clasps on the first premolars or deciduous molars and a labial bow across the permanent incisors. The bow should be supported with a band of acrylic across the labial surfaces of the incisors to increase the anchorage for the finger springs against the mesial surface of the molars to be distalized. These are most successful in the maxillary arch, where there is a dental and skeletal Class I pattern with normal vertical proportions and the regaining of space is by way of uprighting the first permanent molar.

• Full arch fixed appliances.

• Distalizing appliances:

• Distalizing springs or screws.

• Open coil springs.

• Extra-oral headgear.

• Lip bumpers – to upright and distalize lower molars.

Timed extraction of teeth to resolve intra-arch crowding

The total amount of arch length deficiency is the key to planning of timed extractions. For this to be beneficial, a cephalometric analysis should show the child to be growing within a normal pattern and that all the permanent teeth are present radiographically and in the normal order of eruption.

Serial extraction

The purpose of serial extraction is to encourage the early eruption of the first premolars ahead of the permanent canines and should only be considered where there is an arch discrepancy of >4 mm. Serial extraction is usually limited to the upper arch as serial extractions in the lower arch usually results in lingual collapse of the lower anterior segment.

Spacing

Spaces in the deciduous dentition are normal and such spacing indicates an increased chance of good alignment in the permanent dentition. During the early mixed dentition stage, physiological spacing is common in the anterior region with the incisors appearing splayed. As the permanent canines erupt, this will resolve spontaneously and early treatment should not be contemplated.

Dentoalveolar disproportion and tooth size discrepancies can also lead to spacing. Definitive treatment should be delayed until the permanent dentition, when options for space closure through orthodontics or tooth build-ups are available. If ‘cosmetics’ is a concern in the mixed dentition, then crown build-ups of the permanent incisors as a temporary solution, should be considered.

Unusually large spaces may be caused by an enlarged tongue. Isolated true macroglossia is not common and is usually only associated with Beckwith–Wiedemann syndrome. If tongue size is suspected to be enlarged, secondary causes such as increased secretion of growth hormone may also need to be investigated by a paediatrician.

Dentoalveolar disproportion and tooth size discrepancies can also lead to spacing. Definitive treatment is carried out in the permanent dentition, when space closure or tooth build-ups should be considered.

Hypodontia is the term used to describe the congenital absence of one or more teeth. These teeth have not developed from the initiation stage of tooth development (see Chapter 11).

Diagnosis

An understanding of the normal sequence and average age of eruption of permanent teeth will alert the practitioner to the possibility of congenital absence of a tooth or teeth. Any delay in the normal eruption time of permanent teeth or exfoliation of primary teeth should be investigated radiographically. The orthopantomogram (OPG) panoramic radiograph provides a good view for premolars and molars but is often unclear in the incisor region because of the narrow focal trough. It may be necessary to supplement this with either periapical films or, in the maxilla, an anterior occlusal film.

For most children, a radiographic survey at age 7 years will demonstrate the presence or absence of all permanent teeth, except for third molars. It should be noted, however, that there is a large variation, especially in the second premolar region. Third molars are generally not radiographically visible before the age of 9 years. A radiograph will show the tooth follicle before calcification begins, and there is a range in development time between the presentation of the follicle and calcification commencing, especially for second premolars.

Management

Where a permanent tooth is diagnosed as congenitally absent, there are two choices in management:

• Retain the space after loss of the primary tooth and insert a prosthetic replacement.

• Orthodontics to close the space.

The preferred treatment choice will depend on the severity of the condition (number of absent teeth), location of the missing teeth and the underlying skeletal pattern.

Class I patterns

The jaw relationship is normal. If the missing tooth is located in the posterior segments, space closure is often the treatment of choice. Occlusal relationships, however, will dictate the decision. On the other hand, if one or more lateral incisors are missing, the choices are to close spaces and substitute permanent canines for the absent laterals or open the spaces and fire the roots of the adjacent teeth in preparation for implant replacement. Planning such treatment is age-dependent as implants are not indicated until the patient is at least 22 years of age. Opening spaces in preparation for implants as a teenager will require long-term retention of the spaces and root angulations and often will require further orthodontics just prior to the placements of implants due to growth factors.

Class II patterns

This malocclusion is characterized by a smaller mandible with an increased overjet. The preferred option for missing teeth in the maxilla, is to close space and reduce the overjet at the same time. The permanent canines can replace lateral incisors, but size, shape and colour must be considered. Restorative techniques using resin veneers and acid-etch can be used to reshape the canines as lateral incisors, restoring the anatomy of the substituted teeth and providing a balanced smile.

Class III patterns

The maxilla is proportionally smaller than the mandible and there can be a dental cross-bite either anteriorly or posteriorly. If teeth are missing in the lower arch, and the skeletal problem can be camouflaged with orthodontics only, it may be advantageous to close space. Conversely if teeth are missing in the maxilla, space opening and tooth replacement is the preferred option to avoid further constriction of the arch.

Tooth loss due to trauma

Traumatic loss of a maxillary incisor can be treated orthodontically within the same guidelines as those for congenital absence of teeth.

Orthodontic aspects of supernumerary teeth

Development and aetiology

Supernumerary teeth may be found in any part of the dental arch; however, the most frequent sites are in the regions of the maxillary midline and the third molars. Because the supernumerary teeth develop late, they are not often found in the primary dentition and when they do develop with the primary teeth, they usually erupt. Tubercular and inverted supernumerary teeth are most often unerupted, and they commonly delay or inhibit the eruption of the central incisors. Supernumerary teeth in the region of the lateral incisors, either in the primary or permanent dentition, usually erupt into the arch.

Extraction of over-retained primary teeth

The earlier that one can recognize and remove over-retained primary teeth that may be causing ectopic eruption of a succedaneous tooth, the better the chance that a permanent tooth will erupt in a satisfactory position (Figure 14.10). The greatest damage that may result from over-retained primary teeth comes in the wake of ankylosed primary molars.

Ectopic eruption of permanent canines

The incidence of impacted canines in the maxilla is 2% and the majority lie in a palatal position. The anomaly can be associated with small or absent lateral incisors. In about 12% of cases with impacted canines, the lateral incisor root will undergo some resorption.

The normal age of eruption is 11 ± 2 years and the crown should certainly be palpable in the labial sulcus at 9–10 years of age. If the canine is not palpable, further investigation is indicated to check for impaction or ectopic eruption. Intra-oral radiographs taken at right angles to each other and the technique of parallax can be used to localize their position or alternatively an OPG panoramic film. Radiographic scans with cone beam CT are the best for localizing ectopic or impacted permanent canines as these provide a 3D position of the tooth (see Chapter 11).

Interceptive extraction of the deciduous canines can improve the position of the permanent teeth and the maximum improvement will be seen within 12 months (Ericson & Kurol 1988). The success of this approach is reduced, however, if the arch is already crowded (Power & Short 1993).

Ectopic eruption of first permanent molars (Figure 14.12)

This can be an indication of an inadequate arch length, and a radiographic survey is required to confirm the presence of premolar teeth. The permanent teeth may resorb the distal margins of the second primary molars; this is more common in the maxilla.

Extraction of first permanent molars (Figures 14.13, 14.14)

Gross caries involving the first permanent molars poses a difficult dilemma in treatment planning. The early presentation of the patient is essential in obtaining favourable results. The basic questions about whether these teeth should be removed or restored are:

• What is the long-term prognosis for the tooth?

• What is the status of the pulp?

• Are the root apices fully formed?

• Are the third molars present?

Orthodontic appliance systems

Removable appliances

Although removable orthodontic appliances cannot produce all types of tooth movement, they possess several advantages. They are laboratory fabricated and hence require less chair time; are easily removed by the child/patient for oral hygiene and are often low cost. The conventional removable appliance is the Hawley appliance.

Other design considerations

• For successful tooth/teeth movement to occur, the active components of the appliance should produce force in the desired direction whereas anchorage is derived from the acrylic plate that remains stationary.

• The acrylic plate should fit well against the palatal mucosa and must occupy the interdental spaces. The plate should be of even thickness, for strength and to house the retentive components and springs.

• The anchorage of the appliance is derived from palatal tissues, and from the teeth through the clasps.

• The posterior border of the maxillary appliance should be placed anterior to the junction of the hard and soft palate. It should be thin and gently merge with the palatal mucosa.

• The lower appliance should have smooth borders with sufficient relief to accommodate the functioning of the lingual frenum.

Treatment of anterior cross-bites

Up to 10% of children present with cross-bites. Three types of anterior cross-bite may present in the mixed dentition.

Pseudo Class III malocclusion (Figure 14.15)

This pattern occurs where there is a habitual mandibular closure pattern such that the mandible goes into a protrusive bite and thus cross-bite of incisors avoiding traumatic occlusion with lingual position of one or more maxillary incisors. Thus, anterior shift of the mandible can affect the growth of both the maxilla and the mandible with undesirable muscle adaptation. These cases are managed more simply as the primary movement required is to procline the maxillary incisors with a removable appliance or inclined plane until the patient is able to occlude comfortably into a retruded position.

Management

Tongue blade

If there is only one permanent incisor in cross-bite without an excessive overbite, a tongue blade, or paddle pop stick may be used to correct this. The stick is placed lingual to the upper tooth in cross-bite and the patient instructed to close firmly against the stick while it is held in position against the chin. The child should hold it there while biting against it and another person should count to 50 out loud, as in one apple, two apples, etc., for approximately 1 minute. Repeat this six times per day with an interval of at least half an hour. Correction is often complete within a few days.

Inclined planes

Where there is a functional shift of the mandible into an anterior cross-bite, an acrylic inclined plane can be fitted to the lower incisors to restrict the forward posturing and place pressure on the palatal of the maxillary incisors to push them labially. Alternatively, a composite build-up of the lower incisors will mimic the action of an incline plane. (It is preferable to choose a shade of composite resin that is easily distinguished from normal tooth structure to facilitate safe removal).

Treatment is usually complete within a few weeks. This appliance works best where there is a slight increase in overbite, which helps to retain the incisors in positive overjet once the appliance is removed.

Removable appliances (Figure 14.16)

• These appliances should only be used to correct cross-bites of dental origin.

• A modified Hawley appliance can be used in the maxilla to correct one or two teeth in cross-bite.

• Ensure there is adequate space to move the teeth into the desired position and movement will occur rapidly.

• Occlusal surfaces of both the primary and permanent molars should be covered to open the bite and allow free labial movement of the teeth in cross-bite.

• Adams’ clasps are placed on the first permanent molars.

• If the primary molars are present, ball-ended clasps can be fabricated to engage the interproximal areas of these teeth.

Where a single tooth is in cross-bite, a Z-spring placed palatally to the malposed tooth can be used, or if both central incisors are in cross-bite, two springs can be used to provide sweep arms on the palatal surface. Initially, the appliance should be fitted and checked for comfort with the springs passive. The springs are then activated 1–2 mm at a time. The patient is reviewed after 4 weeks to reactivate the springs as required and to check the retention of the appliance.

As with all removable appliances, the success of treatment is reliant on cooperation and compliance. If these qualities can be encouraged and the patient takes responsibility for the wearing of the appliance, treatment will progress satisfactorily. Occasionally, the cross-bite may also be due to a labially placed lower incisor. This must also be corrected, but is dependent on available space. If this is not available, definitive treatment may need to be delayed.

Treatment of posterior cross-bites

A posterior cross-bite is an abnormal, buccolingual relationship of a tooth or teeth when the two dental arches are brought into centric occlusion. There are two types of posterior cross-bite:

Management

• In children with a normally growing mandible, posterior cross-bites should be treated as early as possible to allow normal growth and development of the dental arches and temporomandibular joints. When planning treatment it is important to determine whether the cross-bite is unilateral or bilateral.

• The majority of cross-bites are bilateral but often present as unilateral when the teeth are in full intercuspal position. In these cases, the dental midlines will not be coincident on closing and there will be a deviation of the mandible towards one side at the end on closing.

• When the teeth are closed with the dental midlines coinciding, the posterior segments will be in an edge-to-edge, buccolingual position, reflecting the overall constriction of the maxillary dental arch, and bilateral maxillary expansion is indicated.

Fixed appliances

Slow maxillary expansion – quad helix/nickel titanium expanders

• A quad helix (Figure 14.18) is attached to the palatal surfaces of the cemented first molar bands. This may be hard soldered or removable via palatal tubes welded to the molar bands before cementation.

• The activation of this appliance is controlled by the dentist. This can be done intra-orally using pliers to open the individual helices or by removal of the appliance which is then expanded by hand. The quad helix is activated every 4 weeks and the appliance should be removed every 3 months for extra-oral activation and checking for loose bands or incipient caries.

• The expansion should continue until the molars are overcorrected, then retained with the same appliance for a further 3 months. The cross-bite is usually corrected within 4–6 months.

• The quad helix can be used simultaneously with full bonded appliance treatment.

• Thermal nickel titanium expanders require less adjustment than conventional stainless steel. Quad helix appliances provide a pre-determined amount of expansion. Cooling the expander softens the wire and allows it to be constricted and inserted into lingual tubes on the maxillary molars. As it warms to body temperature, it becomes springy and exerts continuous force on the teeth, thereby causing arch expansion.

• The expanding forces also cause simultaneous derotation of the molars.

Deleterious oral habits

Digit sucking

One of the most common oral activities of the infant and young child is thumb and finger sucking (Figure 14.20). Sucking habits are perfectly normal in infancy. The infant will suck on any object brought into contact with the lips. This reflex behaviour may last for several years. It is an adaptive reflex common to mammals. Because it is a normal activity, thumb and finger sucking may be ignored in infancy. Thumb or finger sucking that is discontinued by age 2–3 years produces no permanent malformation of the jaws or displacement of the teeth. Continued beyond the time that the permanent incisor teeth erupt, it is almost always a factor in producing malocclusion in the anterior portion of the mouth.

The majority of older children who continue thumb sucking have what is termed an ‘empty’ habit. It is just something they have always done. These children are usually receptive to reasons why they should stop and many actually want to give up. A minority, however (especially if the habit has restarted) may have underlying social or psychological problems and these should be investigated.

Control of digit sucking

Chemical means

Chemical therapy employs either hot-tasting, bitter-flavoured preparations or distasteful agents that are applied to the fingers or thumbs. Such things as cayenne pepper, quinine and asafoetida have been used to make the thumb or fingers so distasteful that the child will keep them out of his or her mouth. These preparations are effective with a limited number of children, and only when the habit is not firmly entrenched.

Mouth breathing

Mouth breathing is often associated with recurrent throat infections and nasal blockade. Obstructive mouth breathing can also be associated with severe deviated nasal septum or adenoids. Mouth breathing habit results in vertical growth pattern of the face, narrow maxillary arch, dryness of mouth causing gingivitis around maxillary incisors proclined maxillary incisors and inability to close lips. These facial features have been called ‘adenoid facies’. Timely correction of cause can facilitate oral breathing, which can improve growth pattern of the face. Should the mouth-breathing patient be considered for orthodontics, it should be initiated only after appropriate consultation with an ENT surgeon.

Tongue thrusting

Infantile swallowing habits should change to mature swallowing patterns with the eruption of teeth and the establishment of the occlusion that helps to contain the tongue in the oral cavity lingual to the dental arches during swallowing. ‘Teeth-apart’ swallowing is called a tongue thrust that can lead to open bite. Tongue thrust habits can also be the outcome of clinical malocclusion such as skeletal open bite. Habit breaking appliances in the form of cribs/rakes and swallowing exercises can help restore normal swallowing. A persistent tongue thrust habit can also cause relapse of treated cases of malocclusion leading to spacing/open bite and may require orthognathic surgery to close the open bite.

Correction of developing Class II skeletal malocclusions

Developing Class II skeletal malocclusions may benefit by the use of functional appliances. Functional appliances are those that alter the abnormal functioning of orofacial musculature, thereby bringing about normalization of growth and occlusion (Figure 14.21).

• By using functional appliances, there is an expectation of changes in the facial skeleton by growth modification.

• The simplest functional appliance is the anterior biteplane that can reposition the mandible more anteriorly in a growing child.

• Functional appliances can be fixed or removable.

• Functional appliances can be classified as tooth-borne (active or passive) and tissue-borne, depending upon the structures from which they derive anchorage. All removable functional appliances are tooth-borne, except the Frankel appliance, which is tissue-borne.

• Functional appliances help posture the mandible forward. The degree/amount of vertical and sagittal repositioning may cause variable tissue (muscle) responses.

• Those appliances that displace the mandible within the freeway space are intended to stimulate muscle activity and are called myodynamic appliances.

• Others can cause displacement of the mandible beyond freeway space and rely on passive muscle tension, and are called myotonic appliances.

Clark’s twin block appliance

The twin block appliance is a two-piece functional appliance (Figure 14.22). The upper and lower blocks are made of acrylic and meet each other in the premolar region at an angle of about 70°. This is sufficient to maintain mandibular forward posturing. A child can speak, eat and live with the appliance in place. Being the only full-time functional appliance, it is expected to bring about rapid skeletal, dental and neuromuscular adaptations.

The upper twin block can house an expansion screw as well as springs for individual minor tooth/teeth movement. Hence, while mandibular repositioning is in progress, simultaneous expansion of the maxilla and alignment of minor tooth malpositions can take place, thereby eliminating the need for pre-functional phase treatment, resulting in an overall shorter treatment time.

The twin block appliance offers flexibility of use with fixed appliances that may be required for finishing and detailing in the second phase of occlusal settlement. Hence, the total treatment time could be even shorter.

Summary

Orthodontic assessment of a child requires a careful and detailed clinical examination. A child whose growth is yet to be completed and whose dentition is in a state of flux with several teeth shedding or erupting, needs to be diagnosed as having a state of normal/potentially abnormal or abnormal occlusion. This may require additional diagnostic records to be made, including input from a specialist orthodontist.

Further reading

Crowding

1. Becker A, Kurnei-R’em RM. The effects of infra occlusion: Part I Tilting of the adjacent teeth and local space loss. American Journal of Orthodontics and Dentofacial Orthopedics. 1992;102:256–264.

2. Bolton WA. The clinical application of a tooth-size analysis. American Journal of Orthodontics. 1962;48:504–529.

3. Irwin RD, Herold JS, Richardson A. Mixed dentition analysis: a review of methods and their accuracy. International Journal of Paediatric Dentistry. 1995;5:137–142.

4. Moorres CFA, Chadha JM. Available space for the incisors during dental development: a growth study based on physiological age. Angle Orthodontist. 1965;35:12–22.

5. Papandreas SG, Buschang PH. Physiologic drift of the mandibular dentition following first premolar extractions. Angle Orthodontist. 1993;63:127–134.

6. Staley RN, Kerber PE. A revision of the Hixon and Oldfather mixed dentition prediction method. American Journal of Orthodontics. 1980;78:296–302.

7. Tanaka MM, Johnston LE. The prediction of the size of unerupted canines and premolars in a contemporary orthodontic population. Journal of the American Dental Association. 1974;88:798–801.

Space management

1. Brennan MM, Gianelly AA. The use of the lingual arch in the mixed dentition to resolve incisor crowding. American Journal of Orthodontics and Dentofacial Orthopedics. 2000;117:81–85.

2. Wright GW, Kennedy DB. Space control in the primary and mixed dentitions. Dental Clinics of North America. 1978;22:579–601.

Timed extraction

1. Dale J. Interceptive guidance of occlusion, with emphasis on diagnosis. In: Graber TM, Vanarsdall RL, eds. Orthodontics, current principles and techniques. second ed Philadelphia: Mosby; 1994.

2. Gianelly AA. Crowding: timing of treatment. Angle Orthodontist. 1994;64:415–418.

3. Jacobs S. A reassessment of serial extraction. Australian Orthodontic Journal. 1987;10:90–96.

4. Jacobs SG. Reducing the incidence of palatally impacted maxillary canines by extraction of deciduous canines A useful preventive/interceptive orthodontic procedure. Australian Dental Journal. 1992;37:6–11.

5. Little RM. The effects of eruption guidance and serial extraction on the developing dentition. Pediatric Dentistry. 1987;9:65–70.

6. Mackie IC, Blinkhorn AS, Davies PHJ. The extraction of permanent molars during the mixed-dentition period – a guide to treatment planning. Journal of Paediatric Dentistry. 1989;5:85–92.

Ectopic eruption

1. Brearley LJ, McKibben DH. Ankylosis of primary molar teeth I Prevalence and characteristics. Journal of Dentistry for Children. 1973;40:54–63.

2. Ericson S, Kurol J. Maxillary canines by extraction of the primary canines. European Journal of Orthodontics. 1988;10:283–295.

3. Jacobs SJ. Radiographic localization of unerupted teeth: further findings about the vertical tube shift method and other localization techniques. American Journal of Orthodontics and Dentofacial Orthopedics. 2000;118:439–447.

4. Power SM, Short MBE. An investigation into the response of palatally displaced maxillary canines to the removal of deciduous canines and an assessment of factors contributing to favourable eruption. British Journal of Orthodontics. 1993;20:215–223.

5. Proffit WR, Vig KWL. Primary failure of eruption. American Journal of Orthodontics. 1981;80:173–190.

6. Southall PJ, Graveley JF. Vertical parallax radiography to localize an object in the anterior part of the maxilla. British Journal of Orthodontics. 1989;16:79–83.

Maxillary expansion

1. Bishara SE, Staley RN. Maxillary expansion: clinical implications. American Journal of Orthodontics and Dentofacial Orthopedics. 1987;91:3–14.

2. Fricker JP. Early intervention: the mixed dentition. Annals of the Royal Australasian College of Dental Surgery. 2000;15:124–126.

3. Glineur R, Boucher C, Balon-Perin A. Interceptive treatments (ages 6–10) of transverse deformities: posterior cross-bite. L’Orthodontie Française. 2006;77:249–252.

4. Kennedy DB, Osepchook M. Unilateral posterior cross-bite with mandibular shift: a review. Journal of the Canadian Dental Association. 2000;17:569–573.

5. Thilander B, Wahlund S, Lennartsson B. The effect of early interceptive treatment in children with posterior cross-bite. European Journal of Orthodontics. 1984;6:25–34.

Digit sucking

1. Larsen E. The effect of dummy sucking on the occlusion: a review. European Journal of Orthodontics. 1987;8:127–130.

2. Mitchell EA, Taylor BJ, Ford RP, et al. Dummies and the sudden infant death syndrome. Archives of Disease in Children. 1993;68:501–504.

3. Oulis CJ, Vadiakas GP, Ekonomides J, et al. The effect of hypertrophic adenoids and tonsils on the development of posterior cross-bite and oral habits. Journal of Clinical Pediatric Dentistry. 1994;18:197–201.

Functional appliances

1. Bishara SE, Ziaja RR. Functional appliances: a review. American Journal of Orthodontics and Dentofacial Orthopedics. 1989;95:250–258.

2. Clark WJ. The twinblock technique. American Journal of Orthodontics and Dentofacial Orthopedics. 1988;93:1–18.

3. Twelftree CC. Functional appliances. In: Fricker JP, ed. Orthodontics and dentofacial orthopaedics. Canberra: Tidbinbilla; 1998.

Suggested reading

1. Bishara S. Textbook of orthodontics. Philadelphia: Saunders; 2001.

2. Fricker JP, ed. Orthodontics and dentofacial orthopaedics. Canberra: Tidbinbilla; 1998.

3. Kharbanda OP. Orthodontics: Diagnosis and management of malocclusion and treatment of dentofacial deformities. New York: Elsevier; 2009.