Chapter 16

Health Problems of Early Childhood

Marilyn J. Hockenberry and Lisa Creamer

Chapter Outline

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http://evolve.elsevier.com/Wong/ncic/

Animations

Chickenpox (Varicella Zoster)

Mumps

Case Studies

Bacterial Conjunctivitis

Behaviors Indicative of Future Child Abuse

Chickenpox (Varicella)

Child Abuse

Heavy Metal Poisoning

Ingestion of an Injurious Agent

Salicylate Ingestion

Varicella in Spite of Vaccine

Critical Thinking Exercises

Conjunctivitis

Poisoning

Key Points Audio Summaries

NCLEX Review Questions

Nursing Care Plan

The Child Who Is Maltreated

Spanish/English Translations

WebLinks

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Collection of Specimens, Ch. 27

Compliance, Ch. 27

Controlling Elevated Temperatures, Ch. 27

Growth Failure (Failure to Thrive), Ch. 13

Immunizations, Ch. 12

Infection Control, Ch. 27

Pain Assessment; Pain Management, Ch. 7

Pertussis (Whooping Cough), Ch. 32

Poisoning, Ch. 14

Posttraumatic Stress Disorder, Ch. 18

Rape, Ch. 20

Seizure Disorders, Ch. 37

Skin Lesions, Ch. 18

Stool Specimens, Ch. 27

Infectious Disorders

Communicable Diseases

image The incidence of childhood communicable diseases has declined significantly since the advent of immunizations. The use of antibiotics and antitoxins has further reduced serious complications resulting from such infections. However, infectious diseases do occur, and nurses must be familiar with the infectious agent to recognize the disease and to institute appropriate preventive and supportive interventions (Table 16-1). (See also Chapter 18 for a discussion of nursing care for dermatologic conditions.)

TABLE 16-1

Communicable Diseases of Childhood

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Fig. 16-1 image Chickenpox (varicella). A, Progression of disease. B, Simultaneous stages of lesions. C, Clinical view.
imageAnimation—Chickenpox (Varicella Zoster) (C, From Habif TP: Clinical dermatology: a color guide to diagnosis and therapy, ed 4, St Louis, 2004, Mosby.)

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Fig. 16-2 Erythema infectiosum (fifth disease). (From Habif TP: Clinical dermatology: a color guide to diagnosis and therapy, ed 4, St Louis, 2004, Mosby.)

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Fig. 16-3 Exanthem subitum (roseola infantum).
imageAnimation—Mumps (From Habif TP: Clinical dermatology: a color guide to diagnosis and therapy, ed 4, St Louis, 2004, Mosby.)

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Fig. 16-4 Measles (rubeola). A, Progression of disease. B, Exanthem first appears at the hairline and spreads from head to toe over 3 days. C, Measles ultimately involves the palms and soles. (B and C, From Zitelli BJ, Davis HW: Atlas of pediatric physical diagnosis, ed 5, St Louis, 2007, Mosby; courtesy Dr. Michael Sherlock, Lutherville, Md.)

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Fig. 16-5 Rubella (German measles). A, Progression of rash. B, Clinical view. (B, From Zitelli BJ, Davis HW: Atlas of pediatric physical diagnosis, ed 5, St Louis, 2007, Mosby; courtesy Dr. Michael Sherlock, Lutherville, Md.)

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Fig. 16-6 Scarlet fever.

imageCase Study—Chickenpox (Varicella)

Nursing Care Management

Table 16-1 describes the more common communicable diseases of childhood, their therapeutic management, and specific nursing care. The following is a general discussion of nursing care management for communicable diseases.

Identification of the infectious agent is of primary importance to prevent exposure to susceptible individuals. Nurses in ambulatory care settings, child care centers, and schools are often the first persons to see signs of a communicable disease, such as a rash or sore throat. The nurse must operate under a high index of suspicion for common childhood diseases to identify potentially infectious cases and to recognize diseases that require medical intervention. An example is the common complaint of sore throat. Although most often a symptom of a minor viral infection, it can signal diphtheria or a streptococcal infection, such as scarlet fever. Each of these bacterial conditions requires appropriate medical treatment to prevent serious complications.

When the nurse suspects a communicable disease, it is important to assess:

• Recent exposure to a known case

• Prodromal symptoms (symptoms that occur between early manifestations of the disease and its overt clinical syndrome) or evidence of constitutional symptoms, such as a fever or rash (see Table 16-1)

• Immunization history

• History of having the disease

Immunizations are available for many diseases, and infection usually confers lifelong immunity; therefore the possibility of many infectious agents can be eliminated based on these two criteria.

Prevent Spread: Prevention consists of two components: prevention of the disease and control of its spread to others. Primary prevention rests almost exclusively on immunization. (Chapter 12 discusses the nurse’s role in immunization of children.)

Control measures to prevent spread of disease should include techniques to reduce risk of cross-transmission of infectious organisms between patients and to protect health care workers from organisms harbored by patients. If the child is hospitalized, follow the facility’s policies for infection control. (See Chapter 27.) The most important procedure is hand washing. Persons directly caring for the child or handling contaminated articles must wash their hands and practice effective Standard Precautions in care of their patients.

Instruct the child to practice good hand-washing technique after toileting and before eating. For those diseases spread by droplets, the nurse instructs parents in measures to reduce airborne transmission. The child who is old enough should use a tissue to cover the face during coughing or sneezing; otherwise, the parent should cover the child’s mouth with a tissue and then discard it. Stress the usual hygiene measures of not sharing eating and drinking utensils to the family.

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If a child is admitted to the hospital with an undiagnosed exanthema, institute strict Transmission-Based Precautions (contact, airborne, and droplet) and Standard Precautions until a diagnosis is confirmed. Childhood communicable diseases requiring these precautions include diphtheria, chickenpox, measles, tuberculosis, adenovirus, Haemophilus influenzae type b, influenza, mumps, Mycoplasma pneumoniae infection, pertussis, plague, streptococcal pharyngitis, pneumonia, or scarlet fever (American Academy of Pediatrics, 2009).

Prevent Complications: Although most children recover without difficulty, certain groups are at risk for serious, even fatal, complications from communicable diseases, especially the viral diseases chickenpox and erythema infectiosum (EI) (fifth disease) caused by human parvovirus (HPV) B19.

Children with immunodeficiency—those receiving steroid or other immunosuppressive therapy, those with a generalized malignancy such as leukemia or lymphoma, or those with an immunologic disorder—are at risk for viremia from replication of the varicella-zoster virus (VZV)* in the blood. VZV is so named because it causes two distinct diseases: varicella (chickenpox) and zoster (herpes zoster or shingles). Varicella occurs primarily in children younger than 15 years of age. However, it leaves the threat of herpes zoster, an intensely painful varicella that is localized to a single dermatome (body area innervated by a particular segment of the spinal cord). In children the dermatomes most likely affected by herpes zoster are the cervical and sacral dermatomes (Leung, Robson, and Leong, 2006). Immunocompromised patients and healthy infants younger than 1 year of age (who also have reduced immunity) are at a higher risk for reactivation of VZV causing herpes zoster, probably as a result of a deficiency in cellular immunity (American Academy of Pediatrics, 2009; Galea, Sweet, Beninger, et al, 2008). Complications of herpes zoster virus in children include secondary bacterial infection, depigmentation, and scarring. Postherpetic neuralgia in children is uncommon (Leung, Robson, and Leong, 2006).

image The use of varicella-zoster immune globulin (VariZIG) or immune globulin intravenous (IGIV) is recommended for children who are immunocompromised, who have no previous history of varicella, and who are likely to contract the disease and have complications as a result (American Academy of Pediatrics, 2009). The antiviral agent acyclovir (Zovirax) may be used to treat varicella infections in susceptible immunocompromised persons. It is effective in decreasing the number of lesions; shortening the duration of fever; and decreasing itching, lethargy, and anorexia. Consider oral acyclovir for immunocompromised children without a history of varicella disease, newborns whose mother had varicella within 5 days before delivery or within 48 hours after delivery, and hospitalized preterm infants with significant varicella exposure (American Academy of Pediatrics, 2009).

imageCase Study—Varicella in Spite of Vaccine

Children with hemolytic disease, such as sickle cell disease, are at risk for aplastic anemia from EI. HPV B19 infects and lyses red blood cell precursors, thus interrupting the production of red blood cells. Therefore the virus may precipitate a severe aplastic crisis in patients who need increased red blood cell production to maintain normal red blood cell volumes. Thrombocytopenia and neutropenia may also occur as a result of HPV B19 infection. The fetus has a relatively high rate of red blood cell production and an immature immune system; it may develop severe anemia and hydrops as a result of maternal HPV infection. Fetal death rates as a result of HPV B19 have been estimated to be between 2% and 6% (American Academy of Pediatrics, 2009).

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Refer children at risk for contracting these communicable diseases to the practitioner immediately in case of known exposure or outbreaks.

In the past decade incidence of pertussis has increased, particularly in infants less than 6 months old and in children 10 to 14 years of age. Early clinical manifestations of pertussis in infants may include gagging, coughing, emesis, and apnea; the typical “whoop” associated with the disease is absent (Wood and McIntyre, 2008). In older children the disease may manifest as a common cold (see Table 16-1). There is now a recommendation that children ages 11 to 18 receive a booster pertussis vaccine (Tdap) to prevent the disease. (See Immunizations, Chapter 12.) Because pertussis is contagious, especially among close household members, identify pertussis early and initiate treatment for the child and those who have been exposed. Azithromycin (for infants <1 month) and erythromycin, clarithromycin, or azithromycin are administered to infants and children with pertussis (Wood and McIntyre, 2008).

Prevention of complications from diseases such as diphtheria, pertussis, and scarlet fever requires compliance with antibiotic therapy. With oral preparations, stress the need to complete the entire course of therapy. (See Compliance, Chapter 27.)

Evidence suggests that vitamin A supplementation reduces both morbidity and mortality in measles and that all children with severe measles should receive vitamin A supplements. A single oral dose of 200,000 international units for children at least 1 year old is recommended (use half that dose for children 6 to 12 months of age). The higher dose may be associated with vomiting and headache for a few hours. The dose should be repeated the next day and at 4 weeks for children with ophthalmologic evidence of vitamin A deficiency (American Academy of Pediatrics, 2009).

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Although the risk of vitamin A toxicity from these doses (they are 100 to 200 times the recommended dietary allowance) is relatively low, nurses should instruct parents on safe storage of the drug. Ideally, vitamin A should be dispensed in the age-appropriate unit dose to prevent excessive administration and possible toxicity.

Provide Comfort: Many communicable diseases cause skin manifestations that are bothersome to the child. The chief discomfort from most rashes is itching, and measures such as cool baths (usually without soap) and lotions (e.g., calamine) are helpful.

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When lotions with active ingredients such as diphenhydramine in Caladryl are used, they are applied sparingly, especially over open lesions, where excessive absorption can lead to drug toxicity. Use these lotions with caution in children who are simultaneously receiving an oral antihistamine. Cooling the lotion in the refrigerator beforehand often makes it more soothing on the skin than at room temperature.

To avoid overheating, which increases itching, children should wear lightweight, loose, nonirritating clothing and keep out of the sun. If the child persists in scratching, keep the nails short and smooth or use mittens and clothes with long sleeves or legs. For severe itching, antipruritic medication, such as diphenhydramine (Benadryl) or hydroxyzine (Atarax), may be required, especially when the child has trouble sleeping because of itching. Loratadine, cetirizine, and fexofenadine do not cause drowsiness and may be preferred for urticaria during the day.

An elevated temperature is common, and both antipyretic medicine (acetaminophen or ibuprofen) and environmental manipulation are implemented. (See Controlling Elevated Temperatures, Chapter 27.) The acetaminophen is effective in lowering the fever but does not significantly reduce the symptoms of itching, anorexia, abdominal pain, fussiness, or vomiting.

A sore throat, another frequent symptom, is managed with lozenges, saline rinses (if the child is old enough to cooperate), and analgesics. Because most children are anorectic during an illness, bland foods and increased liquids are usually preferred. During the early stages of the disease, children voluntarily curtail their activity, and although bed rest is beneficial, it should not be imposed unless specifically indicated. During periods of irritability, quiet activity (e.g., reading, music, television, video games, puzzles, coloring) helps distract children from the discomfort.

Support Child and Family: Most communicable diseases are benign, but may produce considerable concern and anxiety for parents. Often the occurrence of a disease such as chickenpox is the first time the child is acutely uncomfortable. Parents need assistance to cope with manifestations of the illness, such as intense itching. The family and child need reassurance that recovery is generally rapid. However, visible signs of the dermatosis may be present for some time after the child is well enough to resume usual activities.

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The occurrence of a communicable disease provides the opportunity to ask parents about the child’s immunization status and reinforce the benefits of vaccines for children.

Conjunctivitis

image Acute conjunctivitis (inflammation of the conjunctiva) occurs from a variety of causes that are typically age related. In newborns conjunctivitis can occur from infection during birth, most often from Chlamydia trachomatis (inclusion conjunctivitis) or Neisseria gonorrhoeae. These organisms, as well as herpes simplex virus (HSV), cause serious ocular damage. In infants recurrent conjunctivitis may be a sign of nasolacrimal (tear) duct obstruction. A chemical conjunctivitis may occur within 24 hours of instillation of neonatal ophthalmic prophylaxis; the clinical features include mild lid edema and a sterile, nonpurulent eye discharge (Fuloria and Kreiter, 2002). In children the usual causes of conjunctivitis are viral, bacterial, allergic, or related to a foreign body. Bacterial infection accounts for most instances of acute conjunctivitis in children. Diagnosis is made primarily from the clinical manifestations (Box 16-1), although cultures of purulent drainage may be needed to identify the specific cause.

BOX 16-1   CLINICAL MANIFESTATIONS OF CONJUNCTIVITIS

Bacterial Conjunctivitis (“Pink Eye”)

Purulent drainage

Crusting of eyelids, especially on awakening

Inflamed conjunctiva

Swollen lids

Viral Conjunctivitis

Usually occurs with upper respiratory tract infection

Serous (watery) drainage

Inflamed conjunctiva

Swollen lids

Allergic Conjunctivitis

Itching

Watery to thick, stringy discharge

Inflamed conjunctiva

Swollen lids

Conjunctivitis Caused by Foreign Body

Tearing

Pain

Inflamed conjunctiva

Usually only one eye affected

imageCase Study—Bacterial Conjunctivitis

imageCritical Thinking Exercise—Conjunctivitis

Therapeutic Management

Treatment of conjunctivitis depends on the cause. Viral conjunctivitis is self-limiting, and treatment is limited to removal of the accumulated secretions. Bacterial conjunctivitis has traditionally been treated with topical antibacterial agents such as polymyxin and bacitracin (Polysporin), sodium sulfacetamide (Sulamyd), or trimethoprim and polymyxin (Polytrim). However, in one study of children with acute infective conjunctivitis treated by placebo versus topical chloramphenicol, there was little difference in cure rates; the authors concluded that most children will get better without antibiotic treatment (Rose, Harnden, Brueggemann, et al, 2005). Fluoroquinolones, approved for children ages 1 year and older, are viewed by ophthalmologists as the best ophthalmic antimicrobial agents available (Lichtenstein, Rinehart, and Levofloxacin Bacterial Conjunctivitis Study Group, 2003). Drops may be used during the day and an ointment at bedtime because the ointment preparation remains in the eye longer but blur the vision. Corticosteroids are avoided because they reduce ocular resistance to bacteria.

Nursing Care Management

Nursing care includes keeping the eye clean and properly administering ophthalmic medication. Remove accumulated secretions by wiping from the inner canthus downward and outward, away from the opposite eye. Warm, moist compresses, such as a clean washcloth wrung out with hot tap water, are helpful in removing the crusts. Compresses are not kept on the eye because an occlusive covering promotes bacterial growth. Instill medication immediately after the eyes have been cleaned and according to correct procedure. (See Chapter 27.)

Prevention of infection in other family members is an important consideration with bacterial conjunctivitis. Keep the child’s washcloth and towel separate from those used by others. Discard tissues used to clean the eye. Instruct the child to refrain from rubbing the eye and to use good hand-washing technique.

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Signs of serious conjunctivitis include reduction or loss of vision, ocular pain, photophobia, exophthalmos (bulging eyeball), decreased ocular mobility, corneal ulceration, and unusual patterns of inflammation (e.g., the perilimbal flush associated with iritis or localized inflammation associated with scleritis). If a patient has any of these signs, refer him or her immediately to an ophthalmologist (Lederman and Lederman, 2003).

Stomatitis

Stomatitis is inflammation of the oral mucosa, which may include the buccal (cheek) and labial (lip) mucosa, tongue, gingiva, palate, and floor of the mouth. It may be infectious or noninfectious and may be caused by local or systemic factors. In children aphthous stomatitis and herpetic stomatitis are typically seen. Children with immunosuppression and those receiving chemotherapy or head and neck radiotherapy are at high risk for developing mucosal ulceration and herpetic stomatitis.

Aphthous stomatitis (aphthous ulcer, canker sore) is a benign but painful condition whose cause is unknown. Its onset is usually associated with mild traumatic injury (biting the cheek, hitting the mucosa with a toothbrush, or a mouth appliance rubbing on the mucosa), allergy, or emotional stress. The lesions are painful, small, whitish ulcerations surrounded by a red border. They are distinguished from other types of stomatitis by healthy adjacent tissues, absence of vesicles, and no systemic illness. The ulcers persist for 4 to 12 days and heal uneventfully.

Herpetic gingivostomatitis (HGS) is caused by HSV, most often type 1, and may occur as a primary infection or recur in a less severe form known as recurrent herpes labialis (commonly called cold sores or fever blisters). The primary infection usually begins with a fever; the pharynx becomes edematous and erythematous; and vesicles erupt on the mucosa, causing severe pain (Fig. 16-7). Cervical lymphadenitis often occurs, and the breath has a distinctly foul odor. In the recurrent form the vesicles appear on the lips, usually singly or in groups. The precipitating factors for the cold sores include emotional stress, trauma (often related to dental procedures), immunosuppression, or exposure to excessive sunlight. The disease can last 5 to 14 days, with varying degrees of severity.

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Fig. 16-7 Primary gingivostomatitis. (From Thompson JM, McFarland GM, Hirsch JE, et al: Mosby’s clinical nursing, ed 5, St Louis, 2002, Mosby.)

Stomatitis may occur as a manifestation of hand-foot-and-mouth disease and herpangina; both manifest with scattered vesicles on the buccal mucosa and are commonly caused by the nonpolio enteroviruses (primarily coxsackieviruses). Children with either hand-foot-and-mouth or herpangina often have poor intake as a result of the mouth sores.

Therapeutic Management

Treatment for all types of stomatitis is aimed at relief of symptoms, primarily pain. Acetaminophen and ibuprofen are usually sufficient for mild cases, but with more severe HGS, stronger analgesics such as codeine may be needed. Topical anesthetics are helpful and include over-the-counter preparations such as Orabase, Anbesol, and Kank-A. Lidocaine (Xylocaine Viscous) can be prescribed for the child who can keep 1 tsp of the solution in the mouth for 2 to 3 minutes and then expectorate the drug. A mixture of equal parts of diphenhydramine elixir and Maalox (aluminum and magnesium hydroxide) provides mild analgesia, antiinflammatory properties, and a protective coating for the lesions. Sucralfate can also be used as a coating agent for oral mucous membranes. Specific treatment for children with severe cases of HGS is the use of antiviral agents such as acyclovir (Phillips, 2008). A recent systematic review found weak evidence that acyclovir is effective in reducing the number of oral lesions, preventing development of new lesions, and decreasing difficulty with eating and drinking (Nasser, Fedorowicz, Khoshnevisan, et al, 2008).

Nursing Care Management

The chief nursing goals for children with stomatitis are relief of pain and prevention of spread of the herpes virus. Analgesics and topical anesthetics are used as needed to provide relief, especially before meals to encourage food and fluid intake. For younger infants and toddlers who cannot swish and swallow, apply the diphenhydramine and Maalox solution with a cotton-tipped applicator before feedings to minimize pain. Educating parents regarding the use of these medications is important to maintain adequate hydration in the child whose mouth is too sore to take liquids. Drinking bland fluids through a straw is helpful in avoiding the painful lesions. Encourage mouth care; the use of a very soft bristle toothbrush or disposable foam-tipped toothbrush provides gentle cleaning near ulcerated areas.

Careful hand washing is essential when caring for children with HGS. Because the infection is autoinoculable, children should keep their fingers out of the mouth; contaminated hands can infect other body parts. Very young children may require elbow restraints to ensure compliance. Articles placed in the mouth are cleaned thoroughly. Newborns and individuals with immunosuppression should not be exposed to infected children.

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When examining herpetic lesions, wear gloves. The virus easily enters breaks in the skin and can cause herpetic whitlow of the fingers.

Because herpes infection is often associated with sexual transmission, explain to parents and older children that HGS is usually caused by type 1 HSV, the type not associated with sexual activity.

Intestinal Parasitic Diseases

Intestinal parasitic diseases, including helminths (worms) and protozoa, constitute the most frequent infections in the world. In the United States the incidence of intestinal parasitic disease, especially giardiasis, has increased among young children who attend daycare centers. Young children are especially at risk because of typical hand-mouth activity and uncontrolled fecal activity.

Various infecting organisms cause intestinal parasitic diseases in humans. This discussion is limited to the two most common parasitic infections among children in the United States: giardiasis and pinworms. Table 16-2 describes the outstanding features of selected helminths that belong to the family of nematodes.

TABLE 16-2

Selected Intestinal Parasites

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General Nursing Care Management

Nursing responsibilities related to intestinal parasitic infections involve assistance with identification of the parasite, treatment of the infection, and prevention of initial infection or reinfection. Laboratory examination of substances containing the worm, its larvae, or ova can identify the organism. Most are identified by examining fecal smears from the stools of persons suspected of harboring the parasite. Fresh specimens are best for revealing parasites or larvae; therefore take collected specimens directly to the laboratory for examination. If this is not possible, place the specimen in a container with a preservative. Parents need clear instructions on obtaining an adequate sample and the number of samples required. (See Stool Specimens, Chapter 27.) In most parasitic infections, other family members, especially children, may be examined to identify those who are similarly affected.

After the diagnosis is confirmed and appropriate treatment is planned, parents need further explanation and reinforcement. Compliance in terms of drug therapy and other measures, such as thorough hand washing, is essential for eradication of the parasite. The family needs to understand the nature of transmission and that in some cases the medication must be repeated in 2 weeks to 1 month to kill organisms hatched since initial treatment.

The nurse’s most important function is preventive education of children and families regarding hygiene and health habits. Thorough hand washing before eating or handling food and after using the toilet is the most important precautionary method. The Family-Centered Care box lists other preventive practices.

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Preventing Intestinal Parasitic Disease

• Always wash hands and fingernails with soap and water before eating and handling food and after toileting.

• Avoid placing fingers in mouth and biting nails.

• Discourage children from scratching bare anal area.

• Use superabsorbent disposable diapers to prevent leakage.

• Change diapers as soon as soiled and dispose of diapers in closed receptacle out of children’s reach.

• Do not rinse cloth or disposable diapers in toilet.

• Disinfect toilet seats and diaper-changing areas; use dilute household bleach (10% solution) or ammonia (Lysol) and wipe clean with paper towels.

• Drink only treated water or bottled water, especially if camping.

• Wash all raw fruits and vegetables and food that have fallen on the floor.

• Avoid growing foods in soil fertilized with human or untreated animal excreta.

• Teach children to defecate only in a toilet, not on the ground.

• Keep dogs and cats away from playgrounds or sandboxes.

• Avoid swimming in pools frequented by diapered children.

• Wear shoes outside.

Giardiasis

Giardiasis is caused by the protozoan Giardia lamblia (also called Giardia intestinalis, Giardia duodenalis, and Lamblia intestinalis). It is the most common intestinal parasitic pathogen in the United States. Child care centers and institutions providing care for persons with developmental disabilities are common sites for urban giardiasis, and the children may pass cysts for months. Also consider giardiasis in those with a history of recent travel to an endemic area (Yoder and Beach, 2007; Shields, Gleim, and Beach, 2008).

The potential for transmission is great, because the cysts—the nonmotile stage of the protozoa—can survive in the environment for months. Chief modes of transmission are person to person; food; and animals, especially puppies. Contaminated water, especially in mountain lakes and streams and swimming or wading pools frequented by diapered infants, are common sources of transmission. In children, person-to-person transmission is the most likely cause. Recent studies indicate swimming pool filters and interactive water fountains to be sites of contamination (Eisenstein, Bodager, and Ginzl, 2008; Shields, Gleim, and Beach, 2008). Although individuals infected with giardiasis may be asymptomatic, common symptoms include abdominal cramps and diarrhea (Box 16-2).

BOX 16-2   CLINICAL MANIFESTATIONS OF GIARDIASIS

Infants and young children:

• Diarrhea

• Vomiting

• Anorexia

• Growth failure (failure to thrive)—if chronic exposure

Children older than 5 years of age:

• Abdominal cramps

• Intermittent loose stools

• Constipation

Stools that are malodorous, watery, pale, and greasy

Spontaneous resolution of most infections in 4 to 6 weeks

Rare, chronic form:

• Intermittent loose, foul-smelling stools

• Possibility of abdominal bloating, flatulence, sulfur-tasting belches, epigastric pain, vomiting, headache, and weight loss

Diagnosis of giardiasis may be made by microscopic examination of stool specimens or duodenal fluid, or by identification of G. lamblia antigens in these specimens by techniques such as enzyme immunoassay (EIA). Because the Giardia organisms live in the upper intestine and are excreted in a highly variable pattern, repeated microscopic examination of stool specimens may be required to identify trophozoites (active parasites) or cysts. Duodenal specimens are obtained by direct aspiration, biopsy, or the string test. In the string test, the child swallows a gelatin capsule with a nylon string attached. Several hours later, the string is withdrawn and the contents are sent for laboratory analysis. With the availability of EIA techniques to identify Giardia antigens in stool specimens, other tests are being used less often.

Therapeutic Management

The drugs of choice for treatment of giardiasis are metronidazole (Flagyl), tinidazole (Tindamax), and nitazoxanide (Alinia). Tinidazole is said to have an 80% to 100% cure rate after a single dose (American Academy of Pediatrics, 2009). Metronidazole and tinidazole have a metallic taste and gastrointestinal side effects, including nausea and vomiting; nitazoxanide has no bitter taste and should be taken with food to avoid gastrointestinal symptoms. Albendazole is also used to treat the disease and reportedly has fewer side effects than metronidazole (American Academy of Pediatrics, 2009).

Nursing Care Management

The most important nursing consideration is prevention of giardiasis and education of parents, child care center staff, and those who assume the daily care of small children. Attention to meticulous sanitary practices, especially during diaper changes, is essential (see Family-Centered Care box and Fig. 16-8). Nurses can play an important role in educating parents of small children and daycare staff regarding appropriate sanitation practices. (See Alternative Child Care Arrangements, Chapter 12.) In addition, discourage young children who are infected or who have diarrhea from swimming in community or private pools until they are infection-free. Lakes and streams may contain high numbers of Giardia spore cysts, which can be swallowed in the water. Discourage children from swimming in stagnant bodies of water, and in water where there are known infected children swimming when there is a high chance of swallowing water. Giardia organisms are said to be resistant to chlorine (Eisenstein, Bodager, and Ginzl, 2008). Encourage parents to take small children to the restroom frequently when swimming, to avoid letting children in diapers in swimming areas, and to change diapers away from the water source. (See also Centers for Disease Control information on recreational water illnesses [www.cdc.gov/healthyswimming].) After children are infected, family education regarding drug administration is essential.

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Fig. 16-8 Prevention of giardiasis, especially in daycare centers, requires sanitary practices during diaper changes, such as discarding paper diapers in a covered receptacle, changing paper covers on the diaper-changing surface, and having facilities for hand washing nearby. note: Soiled cloth diapers and clothing should be stored in a plastic bag for transport home.

Enterobiasis (Pinworms)

Enterobiasis, or pinworms, caused by the nematode Enterobius vermicularis, is the most common helminthic infection in the United States. It is universally present in temperate climatic zones and may infect more than 30% of all children at any one time. Crowded conditions, such as in classrooms and daycare centers, favor transmission.

Infection begins when the eggs are ingested or inhaled (the eggs float in the air). The eggs hatch in the upper intestine, then mature and migrate through the intestine. After mating, adult females migrate out the anus and lay eggs (American Academy of Pediatrics, 2009). The movement of the worms on skin and mucous membrane surfaces causes intense itching. As the child scratches, eggs are deposited on the hands and underneath the fingernails. The typical hand-to-mouth activity of youngsters makes them especially prone to reinfection. Pinworm eggs persist in the indoor environment for 2 to 3 weeks, contaminating anything they contact, such as toilet seats, doorknobs, bed linen, underwear, and food. Except for the intense rectal itching associated with pinworms, the clinical manifestations are nonspecific (Box 16-3).

BOX 16-3   CLINICAL MANIFESTATIONS OF PINWORMS

Intense perianal itching is the principal symptom. Evidence of itching in young children includes:

• General irritability

• Restlessness

• Poor sleep

• Bed-wetting

• Distractibility

• Short attention span

• Perianal dermatitis and excoriation secondary to itching

• If worms migrate, possible vaginal (vulvovaginitis) and urethral infection

Diagnostic Evaluation

Diagnosis is most commonly made from the tape test (see Nursing Care Management). Repeated tests to collect eggs may be necessary, and if there is a possibility that other family members may be infected, perform a tape test on them.

Therapeutic Management

The drugs available for treatment of pinworms include mebendazole (Vermox), pyrantel pamoate (Pin-Rid, Antiminth), and albendazole. The drug of choice is mebendazole, which is safe, effective, and convenient, with few side effects. However, it is not recommended for children younger than 2 years of age. If pyrvinium pamoate is prescribed, advise parents that the drug stains stool and vomitus bright red, as well as clothing or skin that comes in contact with the drug; it is available without prescription and should not be used in children under 2 years without consulting the primary practitioner. Because pinworms are easily transmitted, all household members are treated. The dose of antiparasitic medication should be repeated in 2 weeks to completely eradicate the parasite and prevent reinfection.

Nursing Care Management

Direct nursing care at identifying the parasite, eradicating the organism, and preventing reinfection. Parents need clear, detailed instructions for the tape test. A loop of transparent (not “frosted” or “magic”) tape, sticky side out, is placed around the end of a tongue depressor, which is then firmly pressed against the child’s perianal area. A convenient, commercially prepared tape is also available for this purpose. Pinworm specimens are collected in the morning as soon as the child awakens and before the child has a bowel movement or bathes. The procedure may need to be performed on 3 or more consecutive days before eggs are collected. Parents are instructed to place the tongue blade in a glass jar or loosely in a plastic bag so that it can be brought in for microscopic examination. For specimens collected in the hospital, practitioner’s office, or clinic, place the tape smoothly on a glass slide, sticky side down, for examination.

Adherence to the drug regimen is usually excellent since only one or two doses are needed. The family should be reminded of the need to take a second dose in 2 weeks to ensure eradication of the eggs.

To prevent reinfection, washing all clothes and bed linens in hot water and vacuuming the house may be recommended. However, there is little documentation on the effectiveness of these measures, since pinworms survive on many surfaces. Helpful suggestions include hand washing after toileting and before eating, keeping the child’s fingernails short to minimize the chance of ova collecting under the nails, dressing children in one-piece sleeping outfits, and daily showering rather than tub bathing. Inform families that recurrence is common. Treat repeated infections in the same manner as the first one.

Ingestion of Injurious Agents

image Since the passage of the Poison Prevention Packaging Act of 1970, which requires that certain potentially hazardous drugs and household products be sold in child-resistant containers, the incidence of poisonings in children has decreased dramatically. However, despite these advances, poisoning remains a significant health concern, with most cases (51% in 2007) occurring in children younger than 6 years of age (Bronstein, Spyker, Cantilena, et al, 2008). The home environment lends itself to injury in this vulnerable age-group of children (Dessypris, Dikalioti, Skalkidis, et al, 2009). Although pharmaceuticals such as analgesics, cough and cold preparations, topical preparations, antibiotics, vitamins, gastrointestinal preparations, hormones, and antihistamines are frequently the agents of poisonings, a variety of other substances can still poison children. The most frequently ingested poisons include (Bronstein, Spyker, Cantilena, et al, 2008; Franklin and Rodgers, 2008)*:

imageCase Study—Ingestion of an Injurious Agent

• Cosmetics and personal care products (perfume, cologne, aftershave)

• Cleaning products (hypochlorite [household] bleach, pine oil disinfectants)

• Plants (nontoxic gastrointestinal irritants, oxalates) (Box 16-4)

BOX 16-4   POISONOUS AND NONPOISONOUS PLANTS

Poisonous Plants (Toxic Parts)

Apple (leaves, seeds)

Apricot (leaves, stem, seed pits)

Azalea (all parts)

Buttercup (all parts)

Castor (bean or seeds—extremely toxic)

Cherry (wild or cultivated) (twigs, seeds, foliage)

Daffodil (bulbs)

Dumbcane (dieffenbachia) (all parts)

Elephant ear (all parts)

English ivy (all parts)

Foxglove (leaves, seeds, flowers)

Holly (berries and leaves)

Hyacinth (bulbs)

Ivy (leaves)

Mistletoe* (berries, leaves)

Oak tree (acorn, foliage)

Philodendron (all parts)

Plum (pit)

Poinsettia (leaves)

Poison ivy, poison oak (leaves, stems, sap, fruit, smoke from burning plants)

Pokeweed, pokeberry (roots, berries, leaves [when eaten raw])

Pothos (all parts)

Rhubarb (leaves)

Tulip (bulbs)

Water hemlock (all parts)

Wisteria (seeds, pods)

Yew (all parts)

Nonpoisonous Plants

African violet

Aluminum plant

Asparagus fern

Begonia

Boston fern

Christmas cactus

Coleus

Gardenia

Grape ivy

Jade plant

Piggyback begonia

Piggyback plant

Prayer plant

Rubber tree

Snake plant

Spider plant

Swedish ivy

Wax plant

Weeping fig

Zebra plant


*Eating one or two berries or leaves is probably nontoxic.

Mildly toxic if ingested in massive quantities.

• Foreign bodies, toys, and miscellaneous substances (desiccants, thermometers, bubble-blowing solutions)

Children are exposed to toxic substances more frequently than any other age-group (Eldridge, Van Eyk, and Kornegay, 2007). Many poisonings reflect the ready accessibility of the product in the home, where more than 90% of poisonings occur. A significant number of poisonings take place elsewhere, such as in a grandparent’s or friend’s home, in a school, or in a health care facility.

The developmental characteristics of young children predispose them to poisoning by ingestion. Infants and toddlers explore their environment through oral experimentation. Because their sense of taste is not discriminating at this age, they ingest many unpalatable substances. In addition, toddlers and preschoolers are developing autonomy and initiative, which increase their curiosity and noncompliant behavior. Imitation is also a powerful motivator, especially when combined with lack of awareness of danger.

This section is primarily concerned with the immediate emergency treatment of ingestion of injurious agents. image Box 16-5 summarizes specific management of corrosive, hydrocarbon, acetaminophen, salicylate, iron, and plant poisoning. Because of the importance of lead poisoning among young children, ingestion of lead is discussed separately. Appropriate suggestions for poison prevention are discussed on p. 625 and in Chapter 14.

BOX 16-5   SELECTED POISONINGS IN CHILDREN

Corrosives (Strong Acids or Alkalis)

Drain, toilet, or oven cleaners

Electric dishwasher detergent (liquid, because of higher pH, is more hazardous than granular)

Mildew remover

Batteries

Clinitest tablets

Denture cleaners

Bleach

Clinical Manifestations

Severe burning pain in mouth, throat, and stomach

White, swollen mucous membranes; edema of lips, tongue, and pharynx (respiratory obstruction)

Violent vomiting (hemoptysis)

Drooling and inability to clear secretions

Signs of shock

Anxiety and agitation

Comments

Household bleach is a frequently ingested corrosive but rarely causes serious damage.

Liquid corrosives cause more damage than granular preparations.

Treatment

Inducing emesis is contraindicated (vomiting redamages the mucosa).

Contact poison control center (PCC) immediately. If PCC or medical advice and treatment are not immediately available, it may be appropriate to dilute corrosive with water or milk (usually ≤120 ml [4 oz]).

Do not neutralize. Neutralization can cause an exothermic reaction (which produces heat and causes increased symptoms or produces a thermal burn in addition to a chemical burn).

Maintain patent airway as needed.

Administer analgesics.

Do not allow oral intake.

Esophageal stricture may require repeated dilations or surgery.

Hydrocarbons

Gasoline

Kerosene

Lamp oil

Mineral seal oil (found in furniture polish)

Lighter fluid

Turpentine

Paint thinner and remover (some types)

Clinical Manifestations

Gagging, choking, and coughing

Nausea

Vomiting

Alterations in sensorium, such as lethargy

Weakness

Respiratory symptoms of pulmonary involvement

• Tachypnea

• Cyanosis

• Retractions

• Grunting

Comments

Immediate danger is aspiration (even small amounts can cause bronchitis and chemical pneumonia).

Gasoline, kerosene, lighter fluid, mineral seal oil, and turpentine cause severe pneumonia.

Treatment

Inducing emesis is generally contraindicated

Gastric decontamination and emptying are questionable, even when the hydrocarbon contains a heavy metal or pesticide; if gastric lavage must be performed, a cuffed endotracheal tube should be in place before lavage because of a high risk of aspiration.

Symptomatic treatment of chemical pneumonia includes high humidity, oxygen, hydration, and antibiotics for secondary infection.

Acetaminophen

Clinical Manifestations

Occurs in four stages:

1. Initial period (2 to 4 hours after ingestion)

• Nausea

• Vomiting

• Sweating

• Pallor

2. Latent period (24 to 36 hours)

• Patient improves

3. Hepatic involvement (may last up to 7 days and be permanent)

• Pain in right upper quadrant

• Jaundice

• Confusion

• Stupor

• Coagulation abnormalities

4. Patients who do not die in hepatic stage gradually recover.

Comments

This is the most common accidental drug poisoning in children.

It occurs from acute ingestion.

Toxic dose is 150 mg/kg or greater in children.

Because of multiple formulations and concentrations, chronic acetaminophen toxicity is a significant problem.

Parents should be counseled to read product packaging carefully and to consult a health care professional to avoid inappropriate dosing.

Treatment

Antidote N-acetylcysteine (Mucomyst) can usually be given orally but is first diluted in fruit juice or soda because of the antidote’s offensive odor.

Given as 1 loading dose and usually 17 maintenance doses in different dosages.

May be given intravenously, but use is investigational.

Aspirin (Acetylsalicylic Acid [ASA])

Clinical Manifestations

Acute poisoning

• Nausea

• Disorientation

• Vomiting

• Dehydration

• Diaphoresis

• Hyperpnea

• Hyperpyrexia

• Oliguria

• Tinnitus

• Coma

• Convulsions

Chronic poisoning

• Same as above but subtle onset (often mistaken for viral illness)

• Dehydration, coma, and seizures may be more severe

• Bleeding tendencies

Comments

May be caused by acute ingestion (severe toxicity occurs with 300 to 500 mg/kg).

May be caused by chronic ingestion (i.e., >100 mg/kg/day for 2 or more days); can be more serious than acute ingestion.

Time to peak serum salicylate level can vary with enteric aspirin or the presence of concretions (bezoars).

Treatment

Hospitalization is necessary for severe toxicity.

Emesis, lavage, activated charcoal, or cathartic may be used.

Lavage will not remove concretions of ASA.

Activated charcoal is important early in ASA toxicity.

Sodium bicarbonate transfusions are used to correct metabolic acidosis, and urinary alkalinization may be effective in enhancing elimination; urinary alkalinization is difficult to achieve.

Be aware of the risk for fluid overload and pulmonary edema.

Use external cooling for hyperpyrexia.

Administer anticonvulsants.

Provide oxygen and ventilation for respiratory depression.

Administer vitamin K for bleeding.

In severe cases, hemodialysis (not peritoneal dialysis) is used.

Iron

Mineral supplement or vitamin containing iron

Clinical Manifestations

Occurs in five stages:

1. Initial period (image to 6 hours after ingestion; if child does not develop gastrointestinal symptoms in 6 hours, toxicity is unlikely)

• Vomiting

• Hematemesis

• Diarrhea

• Hematochezia (bloody stools)

• Gastric pain

2. Latency (2 to 12 hours): patient improves

3. Systemic toxicity (4 to 24 hours)

• Metabolic acidosis

• Fever

• Hyperglycemia

• Bleeding

• Shock

• Death (may occur)

4. Hepatic injury (48 to 96 hours)

• Seizures

• Coma

5. Rarely, pyloric stenosis develops at 2 to 5 weeks

Comments

Factors related to frequency of iron poisoning include:

• Widespread availability

• Packaging of large quantities in individual containers

• Lack of parental awareness of iron toxicity

• Resemblance of iron tablets to candy (e.g., M&Ms)

Toxic dose is based on the amount of elemental iron in various salts (sulfate, gluconate, fumarate), which ranges from 20% to 33%; ingestions of 60 mg/kg are considered dangerous.

Treatment

Use emesis or lavage.

For toxic doses lavage may be necessary for all chewable tablets or liquids if spontaneous vomiting has not occurred.

Chelation therapy with deferoxamine is used in severe intoxication (may turn urine red to orange).

If intravenous deferoxamine is given too rapidly, hypotension, facial flushing, rash, urticaria, tachycardia, and shock may occur; stop the infusion, maintain the intravenous line with normal saline, and notify the practitioner immediately.

Plants

Plants listed in Box 16-4

Clinical Manifestations

Depends on type of plant ingested

May cause local irritation of oropharynx and entire gastrointestinal tract

May cause respiratory, renal, and central nervous system symptoms

Topical contact with plants can cause dermatitis

Comments

Plants are some of most frequently ingested substances.

They rarely cause serious problems, although some plant ingestions can be fatal.

Plants can also cause choking and allergic reactions.

Treatment

Induce emesis.

Wash from skin or eyes.

Provide supportive care as needed.

imageCase Study—Salicylate Ingestion

Principles of Emergency Treatment

image A poisoning may or may not require emergency intervention, but in every instance medical evaluation is necessary to initiate appropriate action. Advise parents to call the poison control center (PCC) before initiating any intervention. Parents should post the local PCC telephone number (usually listed in the front of the telephone directory) near each phone in the house (see Critical Thinking Exercise and Emergency Treatment box).

imageCritical Thinking Exercise—Poisoning

image CRITICAL THINKING EXERCISE

Poisoning

Mrs. Berry, a neighbor, calls you. She is upset because her 2-year-old son has eaten several chewable multivitamins with iron. She asks you if she should give her son ipecac. What should you advise her to do?

1. Evidence—Is there sufficient evidence to formulate an answer for Mrs. Berry?

2. Assumptions—Describe some underlying assumptions about the following:

a. What is the best initial response when a child ingests a potentially poisonous substance?

b. What is ipecac?

c. What are the dangers involved in the use of ipecac?

3. What is the priority for nursing care at this time?

4. Does the evidence support your conclusion?

image EMERGENCY TREATMENT

Poisoning

1. Assess the victim:

• Initiate cardiorespiratory support if needed (airway, breathing, circulation).

• Take vital signs; reevaluate routinely.

• Treat associated complications.

2. Terminate exposure:

• Empty mouth of pills, plant parts, or other material.

• Flush eyes continuously with normal saline (or room-temperature tap water at home) for 15 to 20 minutes.

• Flush skin and wash with soap and a soft cloth; remove contaminated clothes, especially if a pesticide, acid, alkali, or hydrocarbon is involved.

• Bring victim of an inhalation poisoning into fresh air.

3. Identify the poison:

• Question the victim and witnesses.

• Look for environmental clues (empty container, nearby spill, odor on breath) and save all evidence of poison (container, vomitus, urine).

• In absence of other evidence, be alert to signs and symptoms of potential poisoning, including symptoms of ocular or dermal exposure.

• Call poison control center or other competent emergency facility for immediate advice regarding treatment.

4. Prevent poison absorption:

• Place child in side-lying, sitting, or kneeling position with head below chest to prevent aspiration.

• Administer activated charcoal if ordered (unless used repeatedly, usual dose is 1 g/kg unless amount of toxin is known), administer drug antidote, or perform gastric lavage.

Based on the initial telephone assessment, the PCC counsels the parents to begin treatment at home or to take the child to an emergency facility. When a call is taken, the name and telephone number of the caller is recorded to reestablish contact if the connection is interrupted. Because most poisonings are managed in the home, expert advice is essential in minimizing adverse effects. When the exact quantity or type of ingested toxin is not known, admission to a health care facility with pediatric emergency treatment services for laboratory evaluation and surveillance during the time after ingestion is critical.

Assessment

The first and most important principle in dealing with a poisoning is to treat the child first, not the poison. This requires an immediate concern for life support. Vital signs are taken, and respiratory or circulatory support is instituted as needed. The child’s condition is routinely reevaluated. Because shock is a complication of several types of household poisons, particularly corrosives, measures to reduce the effects of shock are important, beginning with the ABCs (airway, breathing, circulation) of resuscitation. Establishing and maintaining vascular access for rapid intravascular volume expansion is vital in the treatment of pediatric shock.

The emergency department nurse’s responsibility is to be prepared for immediate intervention with all of the necessary equipment. Because time and speed are critical factors in recovery from serious poisonings, anticipation of potential problems and complications may mean the difference between life and death.

Gastric Decontamination

Although pediatric poison ingestions are common, they rarely result in significant morbidity or mortality (Greene, Harris, and Singer, 2008). Consider using gastrointestinal decontamination (GID) only after careful evaluation of the potential toxicity of the poison and the risks versus benefits. When GID is needed, the immediate treatment is to remove the ingested poison by adsorbing the toxin with activated charcoal, performing gastric lavage, or increasing bowel motility (catharsis). Because of continuing controversy regarding the use of these methods, treat each toxic ingestion individually (Madden, 2008; Eldridge, Van Eyk, and Kornegay, 2007). Specific antidotes may be administered for certain poisonings.

Syrup of ipecac, an emetic that exerts its action through irritation of the gastric mucosa and by stimulation of the vomiting center, is no longer recommended for routine treatment of poison ingestion (American Academy of Pediatrics, 2009; Greene, Harris, and Singer, 2008; Sheffield and Serwint, 2008; Criddle, 2007). Box 16-6 lists the certain situations when ipecac may be of benefit.

BOX 16-6

INDICATIONS FOR IPECAC USE IN THE HOME

Ipecac may be helpful in the home environment after consultation with a health care professional or poison control center in the following circumstances:

• There is no contraindication to ipecac use.

• There is substantial risk of serious toxicity (e.g., colchicines, calcium-channel antagonists, digoxin).

• There is no alternative therapy available or effective means to decrease gastrointestinal absorption.

• There will be a delay of more than 60 minutes before the patient arrives at an emergency department.

• Ipecac can be administered within 30 minutes of the poison ingestion.

• Ipecac will not adversely affect more definitive treatment.

From Greene S, Harris C, Singer J: Gastrointestinal decontamination of the poisoned patient, Pediatr Emerg Care 24(3):176-189, 2008.

image NURSING ALERT

Ipecac is not recommended for routine poison treatment intervention in the home (American Academy of Pediatrics, 2009; Greene, Harris, and Singer, 2008; Sheffield and Serwint, 2008; Criddle, 2007).

Medications such as calcium channel blockers and benzodiazepines either produce a rapid onset of adverse symptoms (e.g., sedation, seizures, coma) or exaggerate the vagal response induced by gagging, which can lead to significant bradycardia. Under either circumstance, uncontrolled vomiting becomes an undesirable and unsafe event.

A more commonly used method of gastrointestinal decontamination is the use of activated charcoal (AC), an odorless, tasteless, fine black powder that adsorbs many compounds, creating a stable complex (Sheffield and Serwint, 2008). AC should be used in the following situations:

• Poison is potentially toxic.

• No contraindications exist to using AC.

• Poison ingested is bound by charcoal.

• Poison is likely to be in the gastrointestinal tract at the time of AC administration.

• Gastrointestinal tract is intact.

• No safer or more effective alternative therapy is available.

AC is mixed with water or a saline cathartic to form a slurry. Slurries are neither gritty nor distasteful but resemble black mud. To increase the child’s acceptance of AC, the nurse should mix it with diet soda and serve it through a straw in an opaque container with a cover (such as a disposable coffee cup and lid) or an ordinary cup covered with aluminum foil or placed inside a small paper bag. In one small study, healthy adolescents preferred the taste of AC mixed with cola or chocolate milk mixture instead of water (Cheng and Ratnapalan, 2007). For small children a nasogastric tube may be required to administer AC (Greene, Harris, and Singer, 2008).

There is discussion of the use of AC in the home for pediatric poison ingestion. The evidence is not clear regarding the risk versus benefit of home AC administration (Eldridge, Van Eyk, and Kornegay, 2007). Potential complications from the use of AC include aspiration (usually in patients with impaired gag reflexes), constipation, and intestinal obstruction (in multiple doses) (Sheffield and Serwint, 2008). Superactivated charcoal products for gastric decontamination are often more palatable and just as effective (Criddle, 2007).

If the child is admitted to an emergency facility, gastric lavage may be performed to empty the stomach of the toxic agent; however, this procedure can be associated with serious complications (gastrointestinal perforation, hypoxia, aspiration) and it is no longer recommended in all cases of ingestion. There is no conclusive evidence that gastric lavage decreases morbidity (Greene, Harris, and Singer, 2008; Sheffield and Serwint, 2008; Criddle, 2007). In addition, gastric lavage may be of little benefit if used later than 1 hour after ingestion (Greene, Harris, and Singer, 2008). Conditions that may be appropriate for the use of gastric lavage include presentation within 1 hour of ingestion of a toxin, ingestion in patient who has decreased gastrointestinal motility, the ingestion of a toxic amount of sustained-release medication, and a massive or life-threatening amount of poison (Madden, 2008; Criddle, 2007). When gastric lavage is used, the patient requires a protected airway, possible sedation, and the largest-diameter tube that can be inserted to facilitate passage of gastric contents. The Evidence-Based Practice box reviews recent literature on the use of gastric lavage in comparison to AC when a child has ingested poison.

EVIDENCE-BASED PRACTICE

Gastric Lavage in Children

Curt Roberts, RN

Danna Salinas, RN, BSN

Ask the Question

What is the effect of gastric lavage in reducing systemic absorption of toxic substances compared with the administration of activated charcoal or forced emesis?

Search for the Evidence

Search strategies

Keywords included gastric lavage, gastric decontamination, activated charcoal, and toxic ingestion. Searches were limited to English articles with human subjects.

Databases used

PubMed, STAT!Ref, UpToDateOnline, CINAHL, EMBASE, D.A.R.E, Cochrane Library, National Guideline Clearinghouse (AHRQ)

Critically Analyze the Evidence

GRADE criteria: Evidence quality moderate; recommendation strong (Guyatt, Oxman, Vist, et al, 2008)

Eddleston, Juszczak, and Buckley (2003) reviewed the literature to determine whether gastric lavage pushes poisons beyond the pylorus to assist with faster elimination of toxins from the body. The review examined two studies designed to measure movement of substances through the stomach and into the small intestine after gastric lavage. One study randomized 40 patients to gastric emptying by forced emesis or gastric lavage and maintained a control group of 20 patients in whom gastric emptying was not necessary. Either radiopaque pellets or radiolabeled water was used as a marker. There were no significant differences in the number of pellets in the small bowel between the emesis group and the control group or between the gastric lavage group and the control group. The second study consisted of five volunteers who were subjected to gastric lavage on three occasions. Less poison was found in the small bowel after gastric lavage than after no intervention. The researchers concluded there was no evidence that gastric lavage drives toxins into the small intestine.

Other studies have demonstrated that gastric lavage is equivalent to forced emesis as a method of gastric emptying (American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists, 2005; Smilkstein, 2002). A randomized crossover study with 12 volunteers who ingested paracetamol 50 mg/kg 1 hour after a standard meal demonstrated that activated charcoal administered within 1 hour of ingestion was more effective than gastric lavage followed by charcoal because of the delay in administration of the activated charcoal (Christophersen, Levin, Hoegberg, et al, 2002). Forced emesis was superior to gastric lavage when the goal was to remove large particles and fragments. However, the literature supports that gastric emptying has limited benefit in gastrointestinal decontamination because administration of activated charcoal appears to be more effective (Greene, Harris, and Singer, 2008; Sheffield and Serwint, 2008; American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists, 2005; Smilkstein, 2002).

Numerous complications are reported with both gastrointestinal lavage and activated charcoal. Complications of orogastric or nasogastric intubation include esophageal tears or perforation, nasal injury, oropharyngeal injury, gastric perforation, and inadvertent tracheal intubation (Eldridge, Van Eyk, and Kornegay, 2007; American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists, 2005; Smilkstein, 2002; Caravati, Knight, Linscott, et al, 2001). The American Academy of Clinical Toxicology and the European Association of Poisons Centers and Clinical Toxicologists (2005) have not recommended the routine use of gastric lavage in the management of toxic ingestions since 1997. Contraindications to the administration of charcoal also exist, including in patients who have ingested corrosive materials and in those at risk for hemorrhage or perforation due to structural abnormalities or recent surgery.

Apply the Evidence: Nursing Implications

Gastric lavage has little or no effect in reducing absorption, especially when used as an intervention more than 1 hour after ingestion. Single-dose or multidose activated charcoal is most effective when administered within 1 hour of ingestion but may have an effect up to 4 hours after ingestion, depending on the substance. Administration of activated charcoal should not be delayed by the use of forced emesis or gastric lavage.

References

American Academy of Clinical Toxicology, European Association of Poisons Centres and Clinical Toxicologists. Position paper: single-dose activated charcoal. J Toxicol Clin Toxicol. 2005;43:61–87.

Caravati, EM, Knight, HH, Linscott, MS, et al. Esophageal laceration and charcoal mediastinum complicating gastric lavage. J Emerg Med. 2001;20(3):273–276.

Christophersen, AB, Levin, D, Hoegberg, LCG, et al. Activated charcoal alone or after gastric lavage: a simulated large paracetamol intoxication. Br J Clin Pharmacol. 2002;53(3):312–317.

Eddleston, M, Juszczak, E, Buckley, N. Does gastric lavage really push poisons beyond the pylorus? A systematic review of the evidence. Ann Emerg Med. 2003;42(3):359–364.

Eldridge, DL, Van Eyk, J, Kornegay, C. Pediatric toxicology. Emerg Med Clin North Am. 2007;25(2):283–308.

Greene, S, Harris, C, Singer, J. Gastrointestinal decontamination of the poisoned patient. Pediatr Emerg Care. 2008;24(3):176–189.

Guyatt, GH, Oxman, AD, Vist, GE, et al. GRADE: an emerging consensus on rating quality of evidence and strength of recommendations. BMJ. 2008;336:924–926.

Sheffield, P, Serwint, JR. Emetics, cathartics and gastric lavage. Pediatr Rev. 2008;29:214–215.

Smilkstein, MJ. Techniques used to prevent gastrointestinal absorption of toxic compounds. In Goldfrank LR, Flomenbaum NE, Lewin NA, et al, eds.: Goldfrank’s toxicologic emergencies, ed 7, New York: McGraw-Hill, 2002.

In a minority of poisonings, specific antidotes are available to counteract the poison. They are highly effective and should be available in all emergency facilities. The supply of antidotes should be checked routinely and replaced as used or according to expiration dates. Antidotes available to treat toxin ingestion include N-acetylcysteine for acetaminophen poisoning, oxygen for carbon monoxide inhalation, naloxone for opioid overdose, flumazenil (Romazicon) for benzodiazepines (diazepam [Valium], midazolam [Versed]) overdose, digoxin immune Fab (Digibind) for digoxin toxicity, amyl nitrate for cyanide, and antivenin for certain poisonous bites.

Prevention of Recurrence

The ultimate objective is to prevent poisonings from occurring or recurring. Home safety education improves poison-prevention practices (Kendrick, Smith, Sutton, et al, 2008). Research supports the effectiveness of parent education on preventing unintentional injuries (Kendrick, Barlow, Hampshire, et al, 2007; Kendrick, Coupland, Mulvaney, et al, 2007). One effective counseling method is first to discuss the difficulties of constantly watching and safeguarding young children (see Family-Centered Care box). In this way the challenging task of raising children can lead to a discussion of injury prevention as part of the parental role. This approach also incorporates contributory causes for the incident, such as inadequate support systems; marital discord; discipline techniques (especially use of physical punishment); and any disruption in the family or family activities, such as vacations, moves, visitors, illnesses, or births. A visit to the home, especially after repeat poisonings, is recommended as part of the follow-up care to assess hazards, including family factors, and to evaluate appropriate injury-proofing measures. One method of identifying risk areas is to ask specific questions or to have the parent complete a questionnaire designed to isolate factors that predispose children to poisoning. Another approach is to encourage parents to bend down to the child’s eye level and survey the home environment for potential hazards. Have the parents try to open cabinets and reach shelves to access poisons.

image FAMILY-CENTERED CARE

Poisoning

A poisoning is more than a physical emergency for the child—it usually represents an emotional crisis for the parents, particularly in terms of guilt, self-reproach, and insecurity in the parenting role. The emergency department is no place to admonish the family for negligence, lack of appropriate supervision, or failure to injury-proof the home. Rather, it is a time to calm and support the child and parents, while unaccusingly exploring the circumstances of the injury. If the nurse prematurely attempts to discuss ways of preventing such an incident from recurring, the parents’ anxiety will block out any suggestions or offered guidance. Therefore it is preferable for the nurse to delay the discussion until the child’s condition is stabilized or, if the child is discharged immediately after emergency treatment, to make a public health referral or send a packet of information.

Passive measures (those that do not require active participation) have been the most successful in preventing poisoning and include using child-resistant closures and limiting the number of tablets in one container. However, these measures alone are not sufficient to prevent poisoning, since most toxic agents in the home do not have safety closures. Therefore active measures (those that require participation) are essential. The Nursing Care Guidelines box lists the guidelines for preventing the occurrence or recurrence of a poisoning.

image Nursing Care Guidelines

Poison Prevention

• Assess possible contributing factors in occurrence of injury, such as discipline, parent-child relationship, developmental ability, environmental factors, and behavior problems.

• Institute anticipatory guidance for possible future injuries based on child’s age and developmental level.

• Initiate referral to appropriate agency to evaluate home environment and need for injury-proofing measures.

• Provide assistance with environmental manipulation, such as lead removal, when necessary.

• Educate parents regarding safe storage of toxic substances.

• Advise parents to take drugs out of sight of children.

• Teach children the hazards of ingesting nonfood items.

• Advise parents against using plants for teas or medicine.

• Discuss problems of discipline and children’s noncompliance and offer strategies for effective discipline.

• Instruct parents regarding correct administration of drugs for therapeutic purposes and to discontinue drug if there is evidence of mild toxicity.

• Advise parents to contact the poison control center, 800-222-1222, or practitioner immediately when a poisoning occurs.

• Tell them to post number of regional poison control center with emergency phone list by telephone.

• They should include by the telephone the home address with nearest cross street in case an ambulance is needed. (In an emergency, family members may not remember the house address, and baby-sitters may not be aware of the information.)

Heavy Metal Poisoning

image Heavy metal poisoning can occur from the ingestion of a variety of substances, the most common being lead. Other sources that are important in terms of children are iron and mercury. Mercury toxicity, a rare form of heavy metal poisoning, has occurred in children from a variety of sources, such as broken thermometers or thermostats, broken fluorescent light bulbs, disk batteries, topical medications, gas regulators, cathartics, and interior latex house paint (Clifton, 2007). Elemental mercury (also called metallic mercury or quicksilver) is nontoxic if ingested and if the gastrointestinal tract is healthy (e.g., has no fistulas). However, mercury is volatile at room temperature and enters the bloodstream after it is inhaled, causing toxicity (tremors, memory loss, insomnia, gingivitis, diarrhea, anorexia, weight loss). The classic form of mercury poisoning is called acrodynia (or “painful extremities”).

imageCase Study—Heavy Metal Poisoning

image NURSING ALERT

Mercury thermometers are no longer recommended because, if they are broken, the inhaled vapors can cause toxicity. To prevent inhalation, clean up spilled mercury quickly, using disposable towels and rubber gloves and washing the hands well afterward.

Heavy metals have an affinity for certain essential tissue chemicals, which must remain free for adequate cell functioning. When metals are bound to these substances, cellular enzyme systems are inactivated. Treatment involves chelation, use of a chemical compound that combines with the metal for rapid and safe excretion.

Lead Poisoning

Poisoning from lead has been a problem throughout history and throughout the world. In the United States the problem became apparent in the early 1900s when white lead was added to paints and when tetraethyl lead was added to gasoline as an antiknock compound. Lead content in paint was decreased in 1950, and in 1978 the use of lead in household paint was banned. The use of lead in paint and leaded gasoline has been banned in the United States. After this change in policy, the average blood lead level (BLL) in the United States for people ages 1 to 74 years dropped from 12.8 mcg/dl in 1980 to 1.9 mcg/dl in 1999 (American Academy of Pediatrics, 2005). However, children continue to be exposed to lead; an estimated 1.6% of U.S. children had BLLs of more than 10 mcg/dl in 2002, and almost 14% had BLLs of 5 to 9 mcg/dl (Levin, Brown, Kashtock, et al, 2008).

Causes of Lead Poisoning

Although there are numerous sources of lead (Box 16-7), in most instances of acute childhood lead poisoning, the source is nonintact lead-based paint in an older home or lead-contaminated bare soil in the yard. Microparticles of lead gain entrance into a child’s body through ingestion or inhalation and, in the case of an exposed pregnant woman, by placental transfer. When measured, a mother’s lead level is nearly the same as that of her unborn child. However, though the level of lead may not be harmful to an adult woman, it can be harmful to the fetus.

BOX 16-7   SOURCES OF LEAD

Lead-based paint in deteriorating condition

Lead solder

Lead crystal

Battery casings

Lead fishing sinkers

Lead curtain weights

Lead bullets

Some of these may contain lead:

• Ceramic ware

• Water

• Pottery

• Pewter

• Dyes

• Industrial factories

• Vinyl mini-blinds

• Playground equipment

• Collectible toys

• Some imported toys or children’s metal jewelry

• Artists’ paints

• Pool cue chalk

Occupations and hobbies involving lead:

• Battery and aircraft manufacturing

• Lead smelting

• Brass foundry work

• Radiator repair

• Construction work

• Bridge repair work

• Painting contracting

• Mining

• Ceramics work

• Stained-glass making

• Jewelry making

Inhalation exposure usually occurs during renovation and remodeling activities in the home, whereas ingestion happens during normal day-to-day play and mouthing activities. Sometimes a child will actually swallow loose chips of lead-based paint because it has a sweet taste. Water and food may also be contaminated with lead. A child does not need to eat loose paint chips to be exposed to the toxin; normal hand-to-mouth behavior, coupled with the presence of lead dust in the environment that has settled over the decades, is the usual method of poisoning (Frazer, 2008; American Academy of Pediatrics, 2005; Erickson and Thompson, 2005).

Because of family, cultural, or ethnic traditions, a source of lead may be a routine part of life for a child. Nurses must educate themselves about the practices of their patients and identify when such products may be a source of lead. The use of pottery or dishes containing lead may be an issue, as may the use of folk remedies for stomachaches or the use of some cosmetics (see Cultural Competence box). Children of immigrants and internationally adopted children may have been exposed to sources of lead before arrival in the United States and should also be carefully evaluated for lead exposure (Woolf, Goldman, and Bellinger, 2007). Other risk factors for having an elevated BLL include living in poverty, being less than 6 years of age, dwelling in urban areas, and living in older rental homes where lead decontamination may not be a priority. Nurses are often in a position to observe or elicit information about these practices and educate families about their potential harm.

image CULTURAL COMPETENCE

Sources of Lead

In some cultures the use of traditional ethnic remedies that contain lead may increase children’s risk of lead poisoning. These remedies include:

Azarcon (Mexico)—For digestive problems; a bright orange powder; usual dose is 0.25 to 1 tsp, often mixed with oil, milk, or sugar or sometimes given as a tea; sometimes a pinch is added to a baby bottle or tortilla dough for preventive purposes

Greta (Mexico)—A yellow-orange powder, used in the same way as azarcon

Paylooah (Southeast Asia)—Used for rash or fever; an orange-red powder given as 0.5 tsp straight or in a tea

Surma (India)—Black powder applied to the inner lower eyelid that is used as a cosmetic to improve eyesight

Unknown ayurvedic (Tibet)—Small, gray-brown balls used to improve slow development; two balls given orally three times a day

Tamarindo jellied, fruit candy (Mexico)—Fruit candy packaged in paper wrappers that contain high lead levels

Lozeena (Iraq)—A bright orange powder used to color meat and rice

Modified from Centers for Disease Control and Prevention: Lead poisoning associated with use of traditional ethnic remedies—California, 1991-1992, MMWR 42(27):521-524, 1993; Centers for Disease Control and Prevention: Lead poisoning associated with imported candy and powdered food coloring—California and Michigan, MMWR 47(48):1041-1043, 1998; Centers for Disease Control and Prevention: Childhood lead poisoning associated with tamarind candy and folk remedies—California, 1992-2000, MMWR 51(31):684-686, 2002.

Pathophysiology and Clinical Manifestations

Lead can affect any part of the body, including the renal, hematologic, and neurologic systems (Fig. 16-9). Of most concern for young children is the developing brain and nervous system, which are more vulnerable than those of an older child or adult. Lead in the body moves via an equilibration process between the blood, the soft tissues and organs, and the bones and teeth. Lead ultimately settles in the bones and teeth, where it remains inert and in storage. This makes up the largest portion of the body burden, approximately 75% to 90%. At the cellular level it competes with molecules of calcium, interfering with the regulating action of calcium. In the brain, lead disrupts the biochemical processes and may have a direct effect on the release of neurotransmitters, may cause alterations in the blood-brain barrier, and may interfere with the regulation of synaptic activity (Lidsky and Schneider, 2006).

image

Fig. 16-9 Main effects of lead on body systems.

There is a relationship between anemia and lead poisoning. Children who are iron deficient absorb lead more readily than those with sufficient iron stores. Lead can interfere with the binding of iron onto the heme molecule. This sometimes creates a picture of anemia, even though the child is not iron deficient. Lead toxicity to the erythrocytes leads to the release of the enzyme erythrocyte protoporphyrin (EP). Because EP is not sensitive to BLLs of less than about 16 to 25 mcg/dl, it is no longer used as a screening test. Therefore the BLL test is currently used for screening and diagnosis. However, elevation of the EP level (>35 mcg/dl of whole blood) is a good indicator of toxicity from lead and reflects the length of exposure and body burden of lead in the individual child.

Although adults have been shown to suffer adverse renal effects from occupational lead exposure, few studies document renal effects in children except at extremely high lead levels. One can hypothesize that lead can affect the renal integrity of children as well as adults. Therefore the renal system of a child is still considered a potential target for the harmful effects of lead.

The lead levels identified in children have declined since the initiation of screening for children at risk for lead poisoning. With earlier intervention, the most prevalent effects have changed. Since the late 1960s, children have rarely died of lead poisoning, and seizures or cognitive impairment have become less likely. However, even mild and moderate lead poisoning can cause a number of cognitive and behavioral problems in young children, including aggression, hyperactivity, impulsivity, delinquency, disinterest, and withdrawal. Long-term neurocognitive signs of lead poisoning include developmental delays, lowered intelligence quotient (IQ), reading skill deficits, visual-spatial problems, visual-motor problems, learning disabilities, and lower academic success. Chronic lead toxicity may also affect physical growth and reproductive efficiency (Woolf, Goldman, and Bellinger, 2007).

image NURSING ALERT

Acute signs of lead poisoning include nausea, vomiting, constipation, anorexia, and abdominal pain. Additional clinical manifestations are hypophosphatemia, glycosuria, and aminoaciduria (Erickson and Thompson, 2005).

Diagnostic Evaluation

Children with lead poisoning rarely have symptoms, even at levels requiring chelation therapy. A diagnosis of lead poisoning is based only on the lead testing of a venous blood specimen from a venipuncture. The collection process is important. Blood must be collected carefully to avoid contamination by lead on the skin. The level of concern for an elevated BLL has dropped from 80 mcg/dl in 1950 to 10 mcg/dl today (Heavey, 2008).

Anticipatory Guidance

Anticipatory guidance lends support to primary prevention efforts. The Centers for Disease Control and Prevention (2005) recommend that the following information be made available to families beginning during prenatal care, at 3 to 6 months, and at 1 year of age:

• Hazards of lead-based paint in older housing

• Ways to control lead hazards safely

• How to choose safe toys

• Hazards accompanying repainting and renovation of homes built before 1978

• Other exposure sources, such as traditional remedies, that might be relevant for a family

There has been recent concern regarding toys and other imported items children play with which were found to contain lead. Parents should carefully evaluate the source of the toy (manufacturer) or item the child may play with and not assume it is safe because it is sold in a U.S. market. The U.S. Consumer Product Safety Commission (www.cpsc.gov) is an excellent resource for parents and caregivers concerned about the safety of a given toy or product that may be harmful.

Screening for Lead Poisoning

When primary prevention fails, secondary prevention screening efforts for elevated BLLs can identify children much earlier than in the past. Guidelines recommend universal or targeted screening (Levin, Brown, Kashtock, et al, 2008). This need is established using blood lead surveillance and other risk factor data collected over time to establish the status and risk of children throughout the state. In areas without available data, universal screening is recommended.

Universal screening should be done at ages 1 and 2 years. Any child between the ages of 3 and 6 years who has not been previously screened should also be tested. Screen any child with risk factors more often.

Targeted screening is acceptable when an area has been determined by existing data to have less risk. Children should be screened when they live in a high-risk geographic area or are members of a group determined to be at risk (e.g., Medicaid recipients), or if their family cannot answer “no” to the following personal risk questions:

• Does your child live in or regularly visit a house that was built before 1950?

• Does your child live in or regularly visit a house built before 1978 with recent or ongoing renovations or remodeling within the past 6 months?

• Does your child have a sibling or playmate who has or did have lead poisoning?

Therapeutic Management

The degree of concern, urgency, and need for medical intervention changes as the lead level increases. Education is one of the most important elements of the treatment process. Several areas that the nurse needs to discuss with the family of every child who has an elevated BLL (≥10 mcg/dl) include (Heavey, 2008; Levin, Brown, Kashtock, et al, 2008):

• The child’s BLL and what it means

• Potential adverse health effects of an elevated BLL

• Sources of lead exposure and suggestions on how to reduce exposure, such as importance of wet cleaning to remove lead dust on floors, window sills, and other surfaces

• Importance of good nutrition in reducing the absorption and effects of lead; for persons with poor nutritional patterns, adequate intake of calcium and iron and importance of regular meals

• Need for follow-up testing to monitor the child’s BLL

• Results of an environmental investigation if applicable

• Hazards of improper removal of lead paint (dry sanding, scraping, or open-flame burning)

Treatment actions vary depending on the child’s BLL. Based on a diagnosis from a venous BLL test, the Centers for Disease Control and Prevention (2002) recommend the following actions:

BLL (mcg/dl) Action
<10 Reassess or rescreen in 1 year. If exposure status changes, do this sooner.
10-14 Provide family with lead poisoning education, follow-up testing, and social service referral if necessary.
15-19 Provide family with lead poisoning education (dietary and environmental), follow-up testing, and social service referral as needed; if BLL persists, initiate actions for BLL of 20 to 44 mcg/dl.
20-44 Provide coordination of care, clinical management, environmental investigation, and lead hazard control.
45-69 Within 48 hours, provide coordination of care and clinical management, including treatment, environmental investigation, and lead hazard control. The child must not remain in a lead-hazardous environment if resolution is to occur.
≥70 Immediately provide medical treatment and begin coordination of care, clinical management, environmental investigation, and lead hazard control.

Chelation Therapy: Chelation is the term used for removing lead from circulating blood and, theoretically, some lead from organs and tissues. It is unclear whether chelation affects lead stores in bones. Although not an antidote in the truest sense, it does serve a similar purpose in that the toxic substance or poison is removed from the body. However, chelation does not counteract any effects of the lead.

Historically two chelating agents have been used consistently: calcium disodium edetate (CaNa2EDTA, or calcium EDTA) and succimer (Chemet, meso-2,3-dimercaptosuccinic acid [DMSA]). British antilewisite (BAL, dimercaprol, dimercaptopropanol) is used in conjunction with EDTA. All the agents have potential toxic side effects and contraindications. Monitor renal, hepatic, and hematologic parameters.

Because of the equilibration process between blood, soft tissues, and other sites in the body, there is often a rebound of the BLL after chelation. After the body burden of lead is reduced enough to stabilize the BLL, rebound will cease. Multiple chelation treatments may be necessary. Adequate hydration is essential during therapy because the chelates are excreted via the kidneys.

BAL must not be used in the presence of a glucose 6-phosphate dehydrogenase deficiency or peanut allergy, nor should it be given in conjunction with iron. It is never used as a single-agent therapy, only in conjunction with EDTA. It must be given only at a deep intramuscular site. EDTA should be given intravenously over several hours or, when necessary to restrict fluids, may be given intramuscularly.

Succimer is given orally over a 19-day course of treatment. The capsule is opened and sprinkled on a small amount of food or may be swallowed whole. Adverse effects include nausea, vomiting, diarrhea, loss of appetite, rash, elevated liver function tests, and neutropenia. Because the chelates are excreted via the kidneys, adequate hydration is essential.

An oral chelating agent, d-penicillamine, is sometimes used to treat lead poisoning, but low doses should be used in children. Monitoring of renal function and blood counts during administration is essential (Woolf, Goldman, and Bellinger, 2007).

Prognosis: Although most of the pathophysiologic effects of lead are reversible, the most serious consequences of both high and low lead exposure are the effects on the central nervous system. In children with lead encephalopathy, permanent brain damage can result in cognitive impairment, behavior changes, possible paralysis, and seizures. However, moderate- to low-dose exposure may also cause permanent neurologic deficits. Increased distractibility, short attention span, impulsivity, reading disabilities, and school failure have been associated with lead exposure. There is some evidence that treatment of moderate levels of lead poisoning can result in cognitive improvement (American Academy of Pediatrics, 2005).

Nursing Care Management

The primary nursing goal in lead poisoning is to prevent the child’s initial or further exposure to lead. For children with low-level exposure, this requires identifying the sources of lead in the environment. Careful history taking is the most useful and most valuable tool and should concentrate on the personal risk questions (see p. 629). Suggestions for reducing lead in the child’s environment are listed in the Community Focus box.

image COMMUNITY FOCUS

Reducing Blood Lead Levels

• Make certain child does not have access to peeling paint or chewable surfaces painted with lead-based paint, especially window sills and wells.

• If a house was built before 1960 (possibly before 1980) and has hard-surface floors, wet mop them at least once per week. Wipe other hard surfaces (e.g., window sills, baseboards). If there are loose paint chips in an area, such as a window well, use a wet disposable cloth to pick up and discard them. Do not vacuum hard-surfaced floors or window sills or wells, since this spreads dust. Use vacuum cleaners with agitators to remove dust from rugs rather than vacuum cleaners with suction only. If a rug is known to contain lead dust and cannot be washed, it should be discarded.

• Wash and dry child’s hands and face frequently, especially before eating.

• Wash toys and pacifiers frequently.

• If soil around home is or is likely to be contaminated with lead (e.g., if home was built before 1960 or is near a major highway), plant grass or other ground cover; plant bushes around outside of house so that child cannot play there.

• During remodeling of older homes, follow correct procedures. Be certain children and pregnant women are not in the home, day or night, until process is completed. After deleading, thoroughly clean house, using cleaning solution to damp mop and dust before inhabitants return.

• In areas where lead content of water exceeds the drinking water standard and a particular faucet has not been used for 6 hours or more, “flush” the cold-water pipes by running the water until it becomes as cold as it will get (30 seconds to >2 minutes). The more time water has been sitting in pipes, the more lead it may contain.

• Use only cold water for consumption (drinking, cooking, and especially for reconstituting powder infant formula). Hot water dissolves lead more quickly than cold water and thus contains higher levels of lead. It is all right to use first-flush water for nonconsumption uses.

• Have water tested by a competent laboratory. This action is especially important for apartment dwellers; flushing may not be effective in high-rise buildings or in other buildings with lead-soldered central piping.

• Do not store food in open cans, particularly if cans are imported.

• Do not use pottery or ceramic ware that was inadequately fired or is meant for decorative use for food storage or service. Do not store drinks or food in lead crystal.

• Avoid folk remedies or cosmetics that contain lead.

• Make certain that home exposure is not occurring from parental occupations or hobbies. Household members employed in occupations such as lead smelting should shower and change into clean clothing before leaving work. Construction and lead abatement workers may also bring home lead contaminants.

• Ensure child eats regular meals, since more lead is absorbed on an empty stomach.

• Ensure child’s diet contains sufficient iron and calcium and not excessive fat.

Modified from Centers for Disease Control and Prevention: Preventing lead poisoning in young children, Atlanta, 2005, The Centers.

For children who undergo chelation therapy, the nurse prepares them for the injections and makes all efforts to reduce injection pain. Chelating agents are administered deeply into a large muscle mass (see Atraumatic Care box). To lessen the pain from EDTA, the local anesthetic procaine is injected with the drug. Rotation of sites is essential to prevent the formation of painful areas of fibrotic tissue. Because EDTA and lead are toxic to the kidneys, keep records of intake and output, and assess the results of urinalysis to monitor renal functioning.

ATRAUMATIC CARE

Lead Chelation Therapy

To lessen the pain from intramuscular injection of calcium disodium edetate (CaNa2EDTA, or calcium EDTA), the local anesthetic procaine is injected with the drug. Apply topical anesthetic cream such as eutectic mixture of local anesthetic (e.g., lidocaine-prilocaine [EMLA]) or LMX4 (4% lidocaine) over the puncture site before the injection of EDTA and British antilewisite (BAL) (time per manufacturer’s guidelines). Administer intravenous EDTA whenever possible.

image NURSING ALERT

Use extreme caution with chelating agents. Incidences of child death from hypocalcemia have been recorded when Na2EDTA was substituted for CaNa2EDTA and used as a chelating agent (Centers for Diseases Control and Prevention, 2006).

image NURSING ALERT

Calcium EDTA is always administered when there is adequate urinary output. Children receiving the drug intramuscularly must be able to maintain adequate oral intake of fluids.

Discharge planning for children with lead poisoning must include thorough education of families regarding safety from lead hazards, clear instructions regarding medication administration and follow-up, and confirmation that the child will be discharged to a home without lead hazards. Although the nurse must use caution to avoid alarming parents unnecessarily, it is important that they know the risk implications for their child’s behavior and cognitive functions. Nurses should observe the development and behavior of children who are hospitalized. Thoroughly evaluate any concerns that are identified. Referral to a child development or speech and language specialist may be necessary.

As in any situational crisis, parents need support and understanding if their child is treated for lead poisoning. Many families at the highest risk for lead poisoning have the fewest resources to comply with measures such as relocation or removal of lead from the environment where the child experiences exposure.

Child Maltreatment

image The broad term child maltreatment includes intentional physical abuse or neglect, emotional abuse or neglect, and sexual abuse of children, usually by adults. It is one of the most significant social problems affecting children. In 2007 Child Protective Service (CPS) agencies in the United States confirmed that an estimated 794,000 children were victims of child maltreatment. Of the confirmed cases, about 11% suffered physical abuse, 8% sexual abuse, 60% neglect, and 4% psychologic maltreatment or emotional abuse. In 2007 there were an estimated 1760 child fatalities as a result of child abuse and neglect (US Department of Health and Human Services, 2009). Reported statistics only partially represent the actual incidence of child maltreatment, since many cases are believed to go unreported.*

imageNursing Care Plan—The Child Who Is Maltreated

Child Neglect

Child neglect is the most common form of maltreatment. More than half of all reported cases are associated with deprivation of necessities, and 34% of deaths from maltreatment are in this group (US Department of Health and Human Services, 2009). Neglect is generally defined as the failure of a parent or other person legally responsible for the child’s welfare to provide for the child’s basic needs and an adequate level of care.

Important contributing factors for child neglect are lack of knowledge of child’s needs, lack of resources, and caregiver substance abuse. For example, neglectful parents often demonstrate poor parenting skills. They may be unaware that an infant needs to be fed every 3 to 4 hours, may not know what to feed the child, and may have insufficient funds to buy food. The most serious lack of knowledge is failure to recognize emotional nurturing as an essential need of children. (See also Growth Failure [Failure to Thrive], Chapter 13.)

Types of Neglect

Neglect takes many forms and can be classified broadly as physical or emotional maltreatment. Physical neglect involves the deprivation of necessities, such as food, clothing, shelter, supervision, medical care, and education. Emotional neglect generally refers to failure to meet the child’s needs for affection, attention, and emotional nurturance.

Neglect may also include lack of intervention for or fostering of maladaptive behavior, such as delinquency or substance abuse. Emotional abuse or psychologic maltreatment, an even more difficult aspect of maltreatment to define, refers to the deliberate attempt to destroy or significantly impair a child’s self-esteem or competence. Emotional abuse may take the form of rejecting, isolating, terrorizing, ignoring, corrupting, verbally assaulting, or overpressuring the child (Nelms, 2001).

Physical Abuse

image The deliberate infliction of physical injury on a child, usually by the child’s caregiver, is termed physical abuse. Legal definitions of physical abuse are found in state and federal statutes. The Child Abuse Prevention and Treatment Act of 1996 defines abuse as “any recent act or failure to act that results in imminent risk of serious harm, death, serious physical or emotional harm of a child (<18 years) by a parent or caregiver who is responsible for the child’s welfare.” Each state defines abuse according to its reporting laws. Minor physical injury is responsible for more reported cases of maltreatment than major physical injury, but major physical abuse causes more deaths. Despite the importance of the problem, a universally accepted definition of what constitutes minor and major physical abuse does not exist. Rather, each state in the United States defines abuse according to its individual reporting laws.

imageCase Study—Child Abuse

Shaken Baby Syndrome

Shaken baby syndrome (SBS) is a serious form of child abuse caused by violent shaking of infants and young children and is one form of abusive head trauma. Physicians commonly use more general terms, including abusive head trauma, inflicted head injury, or neuroinflicted brain injury; these terms do not assume the mechanism of injury, but rather describe the injury itself (Chiesa and Duhaime, 2009). This violent shaking would be easily recognized by others as dangerous (American Academy of Pediatrics, 2001) and is most often a result of the caregiver’s frustration with crying (Castiglia, 2001). Every year in America an estimated 1200 to 1400 children are shaken, and of these victims 25% to 30% die as a result of their injuries. The rest have life-long complications (National Center on Shaken Baby Syndrome, n.d.).

It is important to understand what happens in SBS. Infants have a large head-to-body ratio, weak neck muscles, and a large amount of water in the brain. Violent shaking causes the brain to rotate within the skull, resulting in shearing forces that tear blood vessels and neurons. The characteristic injuries that occur are intracranial bleeding (subdural and subarachnoid hematomas) and, in approximately 85% of cases, retinal hemorrhages, which are classic results of repetitive acceleration-deceleration head trauma (Levin, 2009). Injuries may also include fractures of the ribs and long bones. Most often there are no signs of external injury. SBS is often not an isolated event, and in one study 45% of the children with inflicted traumatic brain injury caused by shaking showed some evidence of prior injury (Ewing-Cobb, Kramer, Prasad, et al, 1998). Victims of SBS can be seen with a variety of symptoms, from generalized flulike symptoms to unresponsiveness with impending death (Miehl, 2005). Many of the presenting symptoms, such as vomiting, irritability, poor feeding, and listlessness, are often mistaken for common infant and childhood ailments. In more severe forms presenting symptoms may include seizures, posturing, alterations in level of consciousness, apnea, bradycardia, or death. The long-term outcomes of SBS include seizure disorders; visual impairments, including blindness; developmental delays; hearing loss; cerebral palsy; and mild to profound mental, cognitive, or motor impairments (Walls, 2006). Nurses can take an active role in prevention of SBS by teaching all caregivers about crying and techniques to cope with inconsolable crying (Carbaugh, 2004).

image NURSING ALERT

Stress to parents the danger of shaking infants (shaking can cause SBS). Education must include coping mechanisms on caring for children with inconsolable crying.

Munchausen Syndrome by Proxy

Munchausen syndrome by proxy (MSBP), also known as medical child abuse or factitious disorder by proxy, is a rare but serious form of child abuse in which caregivers deliberately exaggerate or fabricate histories and symptoms or induce symptoms. It is a form of child maltreatment that may include physical, emotional, and psychologic abuse for the gratification of the caregiver. In most cases the perpetrator is the biologic mother, with some degree of health care knowledge and training. Health care providers can become easily misled and unknowingly enable the perpetrator (Leider, Irving, Mauricio, et al, 2005). Because of the history of symptoms provided by the caregiver, the child endures painful and unnecessary medical testing and procedures. Common symptoms presented are seizures, nausea and vomiting, diarrhea, and altered mental status; they are usually witnessed only by the perpetrator.

Considerations when determining whether a child is a victims of MSBP include:

• Is the child’s condition consistent with the reported history?

• Does diagnostic evidence support the reported history?

• Has anyone other than the caregiver witnessed the symptoms?

• Is treatment being provided primarily because of the caregiver’s demands?

The resolution of symptoms after separation from the perpetrator confirms the diagnosis.

Factors Predisposing to Physical Abuse

image The causes of child abuse are multifaceted. Child maltreatment occurs across all socioeconomic, religious, cultural, racial, and ethnic groups (Goldman, Salus, Wolcott, et al, 2003). Three risk factors are commonly identified in child abuse: parental characteristics, characteristics of the child, and environmental characteristics. However, no single factor or group of factors is predictive of abuse. Rather, the interaction of these factors is thought to increase the risk of abuse occurring in a particular family.

imageCase Study—Behaviors Indicative of Future Child Abuse

Parental Characteristics: Some identified characteristics occur more frequently in parents who abuse their children and are therefore considered risk factors. Younger parents more often are abusers of their children. Single-parent families are at higher risk for abuse, and in single-parent families that include an unrelated partner, the partner is sometimes the abuser, although a biologic parent is most commonly the perpetrator (US Department of Health and Human Services, 2009).

Abusive families are often socially isolated and have few supportive relationships. They often have additional stressors such as low-income circumstances, with little education. Parents with substance abuse problems pose a greater risk for abuse and neglect due to a variety of factors. The additional stressors of substance abuse with the demands of normal care of children create situations where abuse and neglect can occur, since these parents have impaired judgment and may react with violence while under the influence of drugs or alcohol (Wells, 2009). With little or no available support system and concurrent stressors imposed by the child or environment, these parents are vulnerable to additional crises of any nature and may strike out at the child as a method of releasing their frustration and anxiety.

Other factors identified in abusive parents include low self-esteem and little knowledge of appropriate parenting skills. Parenting skills are learned behaviors, and parents who grew up with poor parental role models may have difficulty parenting their own children. Approximately one third of parents who were maltreated as children will subject their children to similar maltreatment (Gara, Allen, Herzog, and other, 2000).

Characteristics of the Child: The onus for child abuse is always on the abuser. However, children who are abused do have some common characteristics. Children from birth to 1 year of age are at highest risk for being abused (US Department of Health and Human Services, 2009). Infants and small children require constant attention and must have all their needs met by others. This can result in parental or caregiver fatigue that results in striking out at the child with physical force, shaking the child, or ignoring the child’s needs.

The physical and emotional demands placed on the parents or caregiver of an unwanted, brain-damaged, hyperactive, or physically disabled child may overwhelm them, resulting in abuse. Disabled children may not understand that abusive behaviors are not appropriate, so do not tell others or defend themselves. Premature infants may be at risk for maltreatment due to failure of parent-child bonding during early infancy, increased physical needs, or irritability. One child may be singled out in an abusive family. Removing that child from the home often places the other siblings at risk for abuse. Therefore no child is safe if left in the abusive environment unless the parents can be helped to learn new parenting skills, to meet the children’s needs, and to release their frustration through alternatives other than attacking their children.

Environmental Characteristics: The environment is a significant part of the potentially abusive situation. A typical environment is one of chronic stress, including problems of divorce, poverty, unemployment, poor housing, frequent relocation, alcoholism, and drug addiction. Increased exposure between children and parents, such as that which occurs in crowded living conditions, also increases the likelihood of abuse.

Although most reporting of abuse has been from lower socioeconomic populations, as stated before, child abuse is not a problem of any one societal group. Stresses imposed by poverty predispose lower socioeconomic families to abusive situations, and abuse in these groups is more likely to be reported. However, concealed crises may also be present in upper-class families. Families who have substitute caregivers such as daycare providers and baby-sitters may also be at risk for child abuse, especially if the family has not fully evaluated the caregiver. Nurses need to be aware of all these factors to identify the less obvious examples of child abuse and neglect.

Sexual Abuse

Sexual abuse is one of the most devastating types of child maltreatment, and estimates indicate that it has increased significantly during the past decade (US Department of Health and Human Services, 2009). Some of the apparent increase is due to increased awareness (Putnam, 2003).

As with all forms of child maltreatment, no universal definition for sexual abuse exists. Definitions of sexual abuse cover a range of acts including involvement of children in sexual acts they do not understand, to which they cannot give consent, or that violate social taboos (Finkel and DeJong, 2001). The Child Abuse and Prevention Act defines sexual abuse as “the use, persuasion, or coercion of any child to engage in sexually explicit conduct (or any simulation of such conduct) or producing any visual depiction of such conduct, or rape, molestation, prostitution, or incest with children.”

Sexual abuse includes the following types of sexual maltreatment (see also Rape, Chapter 20):

Incest—Any physical sexual activity between family members; blood relationship is not required (abusers can include stepparents, unrelated siblings, grandparents, uncles, and aunts); does not include sexual relations between legally sanctioned partners, such as spouses

Molestation—A vague term that includes “indecent liberties,” such as touching, fondling, kissing, single or mutual masturbation, or oral-genital contact

Exhibitionism—Indecent exposure, usually exposure of the genitalia by an adult man to children or women

Child pornography—Arranging and photographing, in any media, sexual acts involving children, alone or with adults or animals, regardless of consent by the child’s legal guardian; also may denote distribution of such material in any form with or without profit

Child prostitution—Involving children in sex acts for profit and usually with changing partners

Pedophilia—Literally means “love of child” and does not denote a type of sexual activity but the preference of an adult for prepubertal children as the means of achieving sexual excitement

Characteristics of Abusers and Victims

Anyone, including siblings and mothers, can be sexual abusers, but a typical abuser is a male whom the victim knows. Offenders come from all levels of society. Adults comprise 80% of sexual abuse offenders, with the remaining 20% being made of adolescents and preadolescents (Johnson, 2004). Many offenders hold full-time jobs, are active in community affairs, and may not have prior criminal records (Finkel and DeJong, 2001). Offenders often are employed (or volunteers) in positions such as teaching or coaching that will bring them into contact with young girls and boys. Child sexual abuse may be generational unless discovered and stopped (Johnson, 2004). Offenders may commit many assaults before being caught.

Incestuous relationships between father or stepfather and daughter are generally prolonged, and the victims are usually reluctant to report the situation because of fear of retaliation and fear that they will not be believed. Typically, incestuous relationships begin later than other forms of child abuse. The eldest daughter is usually abused, but in her absence another sister may be substituted. Sibling incest may also occur. Sexual abuse by relatives with a strong emotional bond with the victim, like a parent, is often the most devastating to the child.

Boys are also victims of both intrafamilial and extrafamilial abuse. Compared with female victims, male victims are much less likely to report abuse, and they may suffer much greater emotional harm from incestuous relationships. Boys are likely to be subjected to anal penetration and oral-genital contact. They often have subtle physical findings and are abused by a father, stepfather, or mother’s boyfriend.

Significant risk factors for child sexual abuse include parental unavailability, lack of emotional closeness and flexibility, social isolation, emotional deprivation, and communication difficulties. Most sexual abuse is committed by men and by persons known to the child, with family members constituting up to two thirds of the perpetrators (Christian, Lavelle, DeJong, et al, 2000). Around 20% to 25% of child sexual abuse cases involve penetration or oral-genital contact. In 2007, over 35% of sexual abuse victim were between 12 to 15 years of age (US Department of Health and Human Services, 2009).

Initiation and Perpetuation of Sexual Abuse

The cycle of sexual abuse often starts insidiously unless it involves an isolated attack, such as rape. Often offenders spend time with the victims to gain their trust before initiating any sexual contact. Most victims are then pressured into being an accessory to the sexual activity through various means and may be unaware that sexual activity is part of the offer. Children may not reveal the truth for fear that their parents would not believe them if they told, especially if the offender is a trusted member of the family. Some fear that they will be blamed for the situation, and many young children with limited vocabulary have difficulty describing the activity when they do have the courage or opportunity to reveal the abuse.

Methods used to pressure children into sexual activity include:

• The child is offered gifts or privileges, or has privileges withheld.

• The adult misrepresents moral standards by telling the child that it is “okay to do.”

• Isolated or emotionally and socially impoverished children are enticed by adults who meet their needs for warmth or human contact.

• The successful sex offender pressures the victim into secrecy by describing it as a “secret between us” that other people would take away if they found out.

• The offender plays on the child’s fears, including the fear of punishment by the offender, fear of repercussions if the child tells, and fear of abandonment or rejection by the family.

Incest most frequently occurs between fathers and daughters, but may be between grandfather and granddaughter, or brother and sister. Brother-sister incest has been found to be just as damaging as father-daughter abuse (Cyr, Wright, McDuff, et al, 2002). Victims may take years to disclose this abuse. However, not all incestuous relationships follow this pattern of silence. Reports of father-daughter incest during child custody conflicts have become more common and have raised serious concerns regarding the possibility of false accusation. Rather than tolerating or denying the child’s sexual abuse, the other parent (usually the mother) is typically the chief accuser.

Nursing Care of the Maltreated Child

A critical responsibility of health professionals is identifying abusive situations as early as possible. Nurses who increase their knowledge of the different types of abuse and neglect and underlying causes will enhance their ability to identify, intervene, and prevent children from maltreatment and neglect (Giardino and Giardino, 2003). The characteristics that may predispose members of some families to commit abuse can serve as a framework for assessing vulnerability, but are never predictive of actual abuse. A careful, detailed history and interview combined with a thorough physical examination are the diagnostic tools needed to identify abuse. Nurses have a special role because they may be the first person to see the child and parent and are the consistent caregivers if the child is hospitalized (see Nursing Care Guidelines box).

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Talking with Children Who Reveal Abuse

• Provide a private time and place to talk.

• Do not promise not to tell; tell them that you are required by law to report the abuse.

• Do not express shock or criticize their family.

• Use their vocabulary to discuss body parts.

• Avoid using any leading statements that can distort their report.

• Reassure them that they have done the right thing by telling.

• Tell them that the abuse is not their fault, that they are not bad or to blame.

• Determine their immediate need for safety.

• Let the child know what will happen when you report.

In interviewing the child and family, the nurse must be careful to avoid biasing the child’s retelling of the events. Some experts suggest that health professionals limit the interview to the child’s physical and mental health concerns and leave topics of the family’s social, legal, or other problems to the police or the CPS (McClain, Giardet, Lahoti, et al, 2000). If this is not possible, make an effort to coordinate the interview process so that all pertinent health care professionals can be present for the interview.

Recognition of abuse or neglect necessitates a familiarity with both physical and behavioral signs that suggest maltreatment (Box 16-8). No one indicator can be used to diagnose maltreatment. It is a pattern or combination of indicators that should arouse suspicion and lead to further investigation. It is important to note that some situations, such as bleeding disorders, osteogenesis imperfecta, or sudden infant death syndrome, may be misinterpreted as abuse. Also, some cultural practices, such as cupping or coin rubbing (see Health Practices, Chapter 2), may mimic physical abuse. Unintentional injuries, such as burns from metal buckles on car seats, bruising from seat belts, or spiral fractures from a twist and fall injury, may also be wrongly diagnosed as abuse. Normal variants, such as mongolian spots and congenital anomalies of genitalia, can be mistaken for abuse.

BOX 16-8   WARNING SIGNS OF ABUSE

• Child has physical evidence of abuse or neglect, including previous injuries.

• History is incompatible with the pattern and/or degree of injury, such as bilateral skull fractures after being dropped.

• Explanation of how injury occurred is vague, or parent or guardian is reluctant to provide information.

• Patient is brought in with minor, unrelated complaint and significant trauma is found.

• Histories are contradictory among caregivers.

• Mechanism of injury provided is not possible given age or developmental level of patient, such as 6-month old turning on hot water.

• Bruising or other injury is present in a nonmobile patient.

• Patient’s affect is inappropriate in relation to extent of injury.

• Evidence of abusive or neglectful parent-child interaction is present.

• Parent, guardian, or custodian disappears after bringing patient in for trauma or patient with suspicious injury is brought in by an unrelated adult.

• Patient has multiple fractures of differing ages.

• There was a delay in seeking care.

• Parent or caregiver discloses that abuse has or may have occurred.

• Patient makes an outcry of abuse or neglect.

Caregiver-Child Interaction

The nurse can use the initial contact with the family to assess the interaction between the caregiver and the child. Observations of the caregivers should include emotional support for the child, attentiveness to the child’s needs, and concern for the child’s injury. Although caregivers and children may vary in responses to a stressful event, note an unusual caregiver-child relationship and factor this into the overall evaluation of the child.

Certain behavioral responses of the parents to their child and to the interviewer should alert the nurse to the possibility of maltreatment. Abusive parents may have difficulty showing concern toward their child. They may be unable or unwilling to comfort the child. Abusers may blame the child for the injuries or belittle him or her for being clumsy or stupid. When interacting with the health care workers, the parent may become hostile or uncooperative. During the child’s hospitalization they may not participate in the child’s care and may show little concern for his or her progress, eventual discharge, or need for follow-up care.

Abused children’s responses to their parents or the injury may also support the suspicion of abuse. Although no one pattern is typical, extremes of behavior may be observed. Children may be unresponsive to the parent or excessively clinging and intolerant of separation. They may be overly attached to the abusive parent, possibly in the hope of preventing any upset that may precipitate anger and another attack. During care of the injury, children may be passive and accepting of the discomfort or uncooperative and fearful of any physical contact. They may avoid eye contact. Some children maintain a wary watchfulness of all strangers; some shy away from strangers as if frightened; others are unusually affectionate and outgoing.

History and Interview

Child Physical Abuse: It is often difficult to distinguish child maltreatment from accidental injuries. Caregivers whose history of events may be deceptive or incomplete and children who are nonverbal may make the assessment more complex. A purposeful, skilled history and appropriate interview questions will help the nurse ensure the right course of action. Knowledge of mechanism of injury and child development is essential. Cases of abuse are often detected when the child or caregiver history of events do not match with physical findings. Children who are verbal can often give a history of the injury. Separating the child from the caregiver may provide a more reliable history. It is important to ask nonleading, open-ended questions. The history should include a narrative of the injury from both caregiver and child (if verbal). Date, time, and location where injury took place along with who was present at the time of the injury are essential questions. Family history for bleeding or bone disorders is important. Box 16-8 outlines areas of history that are concerning for abuse.

Neglect and Emotional Abuse: Each child may manifest different responses to neglect, depending on the situation and developmental age of the child. The goal of the interview is to determine whether the child is in a safe environment and whether the caregiver has the skills and resources to care for the child. It is often difficult to determine whether the circumstances constitute poor parenting skills or true neglect. Box 16-9 lists flags for behaviors to look for in neglected and abused children.

BOX 16-9   CLINICAL MANIFESTATIONS OF POTENTIAL CHILD MALTREATMENT

Physical Neglect

Suggestive Physical Findings

Growth failure

Signs of malnutrition, such as thin extremities, abdominal distention, lack of subcutaneous fat

Poor personal hygiene

Unclean or inappropriate dress

Evidence of poor health care, such as delayed immunization, untreated infections, frequent colds

Frequent injuries from lack of supervision

Suggestive Behaviors

Dull and inactive affect; excessively passive or sleepy

Self-stimulatory behaviors, such as finger sucking or rocking

Begging or stealing food

Absenteeism from school

Substance abuse

Vandalism or shoplifting

Emotional Abuse and Neglect

Suggestive Physical Findings

Growth failure

Eating or feeding disorder

Enuresis

Sleep disorder

Suggestive Behaviors

Self-stimulatory behaviors, such as biting, rocking, sucking

During infancy, lack of social smile and stranger anxiety

Withdrawal from environment and people

Unusual fearfulness

Antisocial behavior, such as destructiveness, stealing, cruelty to animals or people

Extremes of behavior, such as overcompliant and passive, or aggressive and demanding

Lags in emotional and intellectual development, especially language

Suicide attempts

Physical Abuse

Suggestive Physical Findings

Bruises and welts (may be in various stages of healing)

• On face, lips, mouth, back, buttocks, thighs, or areas of torso

• Regular patterns descriptive of object used, such as belt buckle, hand, wire hanger, chain, wooden spoon, squeeze or pinch marks

• May be present in various stages of healing

Burns

• On soles, palms, back, or buttocks

• Patterns descriptive of object used, such as round cigar or cigarette burns; sharply demarcated areas from immersion in scalding water; rope burns on wrists or ankles from being bound; burns in the shape of an iron, radiator, or electric stove burner

• Absence of “splash” marks and presence of symmetric burns

• Stun gun injury: lesions circular, fairly uniform (≤0.5 cm), and paired about 5 cm apart

Fractures and dislocations

• Skull, nose, or facial structures

• Injury denoting type of abuse, such as spiral fracture or dislocation from twisting of an extremity or whiplash from shaking the child

• Multiple new or old fractures in various stages of healing

Lacerations and abrasions

• On backs of arms, legs, torso, face, or external genitalia

• Unusual symptoms, such as abdominal swelling, pain, and vomiting from punching

• Descriptive marks such as from human bites or pulling out of hair

Chemical

• Unexplained repeated poisoning, especially drug overdose

• Unexplained sudden illness, such as hypoglycemia from insulin administration

Suggestive Behaviors

Wary of physical contact with adults

Apparent fear of parents or going home

Lying very still while surveying environment

Inappropriate reaction to injury, such as failure to cry from pain

Lack of reaction to frightening events

Apprehension when hearing other children cry

Indiscriminate friendliness and displays of affection

Superficial relationships

Acting-out behavior, such as aggression, to seek attention

Withdrawal behavior

Sexual Abuse

Suggestive Physical Findings

Bruises, bleeding, lacerations, or irritation of external genitalia, anus, mouth, or throat

Torn, stained, or bloody underclothing

Pain on urination or pain, swelling, and itching of genital area

Penile discharge

Sexually transmitted infection, nonspecific vaginitis

Difficulty in walking or sitting

Unusual odor in the genital area

Recurrent urinary tract infections

Presence of sperm

Pregnancy in young adolescent

Suggestive Behaviors

Sudden emergence of sexually related problems, including excessive or public masturbation, age-inappropriate sexual play, promiscuity, or overtly seductive behavior

Withdrawn behavior, excessive daydreaming

Preoccupation with fantasies, especially in play

Poor relationships with peers

Sudden changes, such as anxiety, loss or gain of weight, clinging behavior

In incestuous relationships, excessive anger at mother for not protecting daughter

Regressive behavior, such as bed-wetting or thumb sucking

Sudden onset of phobias or fears, particularly fears of the dark, men, strangers, or particular settings or situations (e.g., fear of leaving the house or staying at the daycare center or the baby-sitter’s house)

Running away from home

Substance abuse, particularly of alcohol or mood-elevating drugs

Profound and rapid personality changes, especially extreme depression, hostility, and aggression (often accompanied by social withdrawal)

Rapidly declining school performance

Suicidal attempts or ideation

Sexual Abuse: An essential component to identifying sexual abuse is the interview. Several dynamics may impede the child’s revelation of sexual abuse. Child sexual abuse is often perpetrated by someone known to the child, including family members. In some cases, the child may have been sworn to secrecy. The child may have been told that no one will believe the story or that his or her family would be harmed if he or she told someone about the abuse. Small children may imitate behaviors they have had perpetrated on themselves or have seen others do. The nurse must be able to recognize normal, age-related sexual curiosity and self-stimulating behaviors. Typically, children do not act out specific details of the sexual act or perform intrusive acts on others unless they have sexual knowledge beyond their normal age-related development. (Johnson, 2004).

Children’s reports of sexual abuse may vary from contradictory stories to unwavering versions of the experience. Stories that sound contradictory may reflect the child’s experiences in several instances of abuse. Also, children who repeatedly tell identical facts may have been prompted to do so.

Increasing evidence suggests that the types of interrogation children are exposed to after reports of sexual abuse shape their thinking. To avoid biasing the interaction, nurses must be skillful interviewers when questioning children who may be victims of abuse. Medical records should include verbatim statements made by the child and interviewer that reflect appropriate nonleading questions and statements (Hornor, 2001; McClain, Girardet, Lahoti, et al, 2000). The child may not be emotionally ready to discuss the abuse. Establishing rapport with the child is essential to gaining his or her trust. Interviews should not be rushed. Engaging the child in play activities while encouraging conversation may help the child discuss the abuse. It may take several interviews or psychologic counseling for the child to be forthcoming about the abuse. Information regarding the last sexual contact is important because it determines the need for a forensic evaluation. Children who have been sexually abused within the past 72 to 96 hours should be considered for forensic testing.

Unfortunately, there is no typical profile of the victim, and the nurse must have a high index of suspicion to identify these children. Physical signs vary and may include any of those listed for sexual abuse. The victim may exhibit various behavioral manifestations, but none of these behaviors is diagnostic. When abused children exhibit these behaviors, the signs may be incorrectly attributed to the normal stresses of childhood, especially in older school-age children or adolescents. Even signs considered most predictive of sexual abuse, such as certain genital findings, sexually inappropriate behavior for age, enactment of adult sexual activity, and intense focus on sexual activity (e.g., masturbation), do not always indicate that sexual abuse has occurred. Conversely, abused children may not demonstrate more knowledge of sexual activity than nonabused children. However, one difference in the abused children’s explanation of sexual activity may be unusual affective responses. For example, abused children may have an increased incidence of sleep disorders, temper tantrums, and depression (Calam, Horne, Glasgow, et al, 1998).

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When children report potentially sexually abusive experiences, take their reports seriously, but also cautiously to avoid alarming the child or falsely accusing someone.

Physical Assessment

Child Physical Abuse: The goal of the physical assessment for child physical abuse is identification of all injuries. A system approach ensures the whole body is evaluated. In instances of severe abuse and injuries, the assessment should begin with a rapid assessment of airway, breathing, circulation, and neurologic systems. A systematic head-to-toe examination follows. Attention to areas often overlooked, such as the scalp, behind the ears, and the frenulum, is essential. The child’s exterior genital area and posterior surface should be completely examined.

Record the location and a detailed description of all injuries. Note color, size, and location of all bruising. Burn documentation should include location, pattern, demarcation lines, and presence of eschar or blisters. Diagrams of the injuries using a body diagram form are helpful. If possible, obtain photographs of the injuries using a measurement tool.

Not all forms of physical abuse have obvious signs. Intraabdominal organ injury from blunt trauma to the abdomen can occur without signs of external abdominal bruising. Nurses should consider intraabdominal injury in infants and children who have any other signs of abuse.

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Incompatibility between the history and the injury is probably the most important criterion on which to base the decision to report suspected abuse.

All evidence collected must adhere to strict guidelines for legal purposes; chain of custody must be appropriately maintained with local law enforcement personnel. Documentation on the chain of custody form should include the names of persons collecting and receiving evidence (such as photographs and DNA samples), types of evidence collected and received, and date of receipt (Kaczor, Pierce, Makoroff, et al, 2006).

Neglect and Emotional Abuse: Neglect from deprivation of necessities is easier to identify than emotional neglect or psychologic maltreatment because physical signs are usually evident. Assessment of the child’s height, weight, nutritional status, hygiene, and age-appropriate interactions is important for the overall picture of potential neglect. Emotional maltreatment may be readily suspected, but it is difficult to substantiate. Physical signs are often nonspecific, and nurses must rely on behavioral indicators, which range from depression to acting-out behavior, to help identify a possibly abusive situation. Any persistent and unexplained change in the child’s behavior is an important clue to possible emotional abuse.

Sexual Abuse: Identifying instances of sexual abuse is particularly difficult because, often, few if any obvious physical indications of the activity exist. Physical signs vary and may include any of those listed in Box 16-9 for sexual abuse. The goal of the physical examination is to document genital findings. In most cases, the genital examination is normal, which does not mean that sexual abuse did not occur. Fondling or genital-to-genital contact without penetration may leave no physical findings. Forensic evidence obtained directly from a prepubertal victim’s body diminishes greatly after 24 hours, with the best chance for evidence collection coming from bed linens or the child’s underwear (Christian, Lavelle, DeJong, et al, 2000). The female genital examination should include a description of the vulva, hymen, and surrounding tissue. Abnormal findings of concern are injuries to the posterior vulva or the lower half of the hymeneal ring, or abrasions, bruising, or bleeding of the genital or anal tissue. It is often helpful to use a magnifying instrument (colposcope) to detect subtle injuries. There are many variants of normal findings for female genital anatomy, so it is recommended that the examination be done by a practitioner experienced with these type of cases. Contrary to popular myth, the size of the hymeneal opening is not predictive of the likelihood of sexual abuse (Christian and Rubin, 2002). For male victims, swelling, abrasions, or bruising of the genital tissue raises concerns for abuse. Examine the anal area for symmetry, tone, fissures, or scars. Genital tissue heals very quickly and most often without scars. Therefore, unless the child is seen within a few days of injury, the genital tissue may appear normal. In addition, the vaginal and anal mucosa is elastic; therefore penetration without disruption of tissue is possible. This defies another myth that there is always evidence of female virginity. Consider the collection of specimens for determining the presence of sexually transmitted infections, which may have been contracted during the sexual contact.

A number of nursing diagnoses are prominent in the nursing care of the maltreated child and family, and others specific to individual cases become evident. The Nursing Care Plan on p. 640 describes the expected outcomes.

Nursing Care Management

Protect Child from Further Abuse: Initially, identification of instances of suspected abuse or neglect is essential. The nurse may come in contact with abused children in an emergency department, practitioner’s office, home, daycare center, or school.

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The priority is to remove the child from the abusive situation to prevent further injury.

All states and provinces in North America have laws for mandatory reporting of child maltreatment. Suspected child abuse is reported to the local authorities.* Referrals usually come to the state child welfare department and are assigned to a caseworker in an agency such as CPS. After a referral has been made, a caseworker is assigned to investigate the report. Based on the findings, the child is left in the home or temporarily removed.

A court proceeding may be necessary before the child can be placed outside the home or when parental rights are to be terminated. When the courts are involved, they usually require firsthand testimony by the referring parties. Nurses may be subpoenaed to appear in court, or their notes may be introduced as evidence in court hearings. Accurate and factual documentation is essential. Behaviors are described, not interpreted, and are recorded daily to establish a progress record (see Nursing Care Guidelines box). Conversations among the nurse, child, and parent are recorded verbatim as much as possible.

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Recording Assessment Data in Suspected Abuse

History of Injury

Date, time, and place of occurrence

Sequence of events with recorded times

Presence of witnesses, especially person caring for child at time of incident

Time lapse between occurrence of injury and initiation of treatment

Interview with child when appropriate, including verbal quotations and information from drawing or other play activities

Interview with parent, witnesses, or other significant persons, including verbal quotations

Description of parent-child interactions (verbal interactions, eye contact, touching, parental concern)

Name, age, and condition of other children in home (if possible)

Physical Examination

Location, size, shape, and color of bruises; approximate location, size, and shape on drawing of body outline

Distinguishing characteristics, such as a bruise in the shape of a hand or a round burn (possibly caused by cigarette)

Symmetry or asymmetry of injury; presence of other injuries

Degree of pain; any bone tenderness

Evidence of past injuries; general state of health and hygiene

Developmental level of child; screening test (see Developmental Assessment, Chapter 6)

Support Child: Children suspected of being abused are often hospitalized for medical management of their injuries and to allow further assessment of their safety needs. The needs of these children are the same as those of any hospitalized child. The child should be treated as a child with the usual physical needs, developmental tasks, and play interests—not as a victim of abuse. The goal of the nurse-child relationship is to provide a role model for the parents in helping them to relate positively and constructively to their child and to foster a therapeutic environment for the child in his or her reprieve from the abusing situation.

Support Family: The nurse also encourages the child’s relationship with nonoffending parents. The nurse does not become a substitute parent, but rather acts as a role model for parents in helping them to relate positively and constructively to their child. When parental ignorance of childrearing practices has played a part in the abuse, the nurse can educate the parent regarding children’s physical and emotional needs. Because of the parents’ own childrearing, they may not be aware of nonviolent methods of discipline, such as time-out. They may also need help in dealing with their frustration so that they do not vent anger on the child. Because these parents may be sensitive to criticism or resistant to authority figures, teaching is implemented through demonstration and example rather than through lecturing. Praise any competent parenting abilities they demonstrate to promote their sense of parental adequacy.

Advise family members to encourage the child to resume normal activities and observe the child for signs of distress. (See Posttraumatic Stress Disorder, Chapter 18.) Children express their feelings primarily through behavior. Parents should be alert for changes in behavior that indicate distress resulting from the incident, such as remaining in the house, refusal to go to school, changes in sleeping patterns, and frequency of dreams and nightmares.

Referral to appropriate social service agencies is also essential. Many abusive parents live in poverty, and the daily stresses imposed by their circumstances are overwhelming. Seek resources for financial aid, improved housing, and child care. Self-help groups also provide important services. Groups such as Parents Anonymous* (a group for parents who have abused or fear that they may abuse their child, but only in terms of physical abuse, not sexual abuse).

Plan for Discharge: Discharge planning should begin as soon as the legal disposition for placement has been decided, which may be temporary foster home placement, return to the parents, or permanent termination of parental rights. The latter is the most drastic solution, but it is necessary in situations of life-threatening abuse. Whenever children are sent to a foster home or juvenile institution, they must be allowed an opportunity to express their feelings. No matter how severe the abuse, they usually mourn the loss of their parents. They need help to understand why they must not return home and that this new home is in no way a punishment. Whenever possible, foster parents are encouraged to visit in the hospital, and the nurse should take an active role in helping these new parents understand the child, as well as the child’s health care needs, since studies have shown that the health care needs of children in foster care often go unmet (Mekonnen, Noonan, and Rubin, 2009).

Prevent Abuse: Prevention of child maltreatment has been an extremely difficult goal. However, nurses have played an important role in such programs. For example, home visits to primiparas who were either teenagers, unmarried, or of low socioeconomic status was noted to be an effective preventive measure (Eckenrode, Ganzel, Henderson, et al, 2000; McMillian, 2000). The nurses provided information on normal child growth and development and routine health care needs, served as informal support persons, and referred families to appropriate services when a need for assistance was identified. The Nurse-Family Partnership is one such program that has demonstrated evidence-based interventions resulting in the prevention of child maltreatment (Donelan-McCall, Eckenrode, and Olds, 2009).

Nurses in a variety of settings can implement similar activities. For example, nurses in prenatal clinics can prepare expectant families for adjustment to parenthood. Nursery and postpartum nurses can foster the attachment process by encouraging parents to hold and look at their infant, as well as teaching coping mechanisms for prolonged crying. Nurses in neonatal intensive care units can minimize the effects of separation by encouraging parents to visit and can help parents become comfortable caring for their child. Nurses in ambulatory settings can teach parents appropriate methods of bathing, feeding, toileting, disciplining, and preventing injuries, while stressing the normal needs and developmental characteristics of children. Nurses must be sensitive to parental needs for attention, reassurance, and reinforcement, and refer parents to community services and self-help groups.

Unlike preventive efforts for neglect and physical abuse, which have been aimed at the potential offender, prevention of child sexual abuse has centered on education of children to protect themselves. Materials are available for parents that describe sexual abuse and its prevention. Helpful games such as “What if the baby-sitter wants to wrestle and hug but tells you to keep it a secret?” can be used to explore dangerous situations in advance and help children learn the importance of saying “no.” They need reassurance that no matter what the other person says or does, the parents want to know about it and will not punish them. Even if children participate in the activity before telling the parents, they must be reassured that it was not their fault. It is equally important to teach children safety in terms of potential risk situations. Several suggestions for parents regarding protecting and educating children against possible molestation are presented in the Family-Centered Care box. The nurse is frequently in a position to discuss the topic of abuse with parents and to provide guidelines. In addition, parents need to be made aware that “nice” people, including friends and relatives, can be offenders; parents should carefully observe how others act toward the child. A sudden change in the child’s behavior and a response such as “I don’t like Uncle anymore” are clues to investigate the relationship. In the event of any doubt, prevent further solitary encounters with this person and the child. It is sometimes to the child’s great misfortune that parents do not take certain comments seriously, such as “He hugs me too tight” or “I don’t want to go with him.” Casual parental statements such as “He just loves you” or “You do whatever adults tell you to do” can place children in jeopardy. Health professionals must alert parents to such dangers and guide them toward an appreciation of the problem, providing concrete guidelines toward child education and protection (see Nursing Care Plan).

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Preventing or Dealing with Sexual Abuse of Children

Sexual assault of children is much more common than most people realize. It may be preventable if children have good preparation. To provide protection and preparation:

• Pay careful attention to who is around children. (Unwanted touch may come from someone liked and trusted.)

• Back up a child’s right to say no.

• Encourage communication by taking seriously what children say.

• Take a second look at signals of potential danger.

• Refuse to leave children in the company of those not trusted.

• Include information about sexual assault when teaching about safety.

• Provide specific definitions and examples of sexual assault.

• Remind children that even “nice” people sometimes do mean things.

• Urge children to tell about anybody who causes them to be uncomfortable.

• Prepare children to deal with bribes, threats, and possible physical force.

• Virtually eliminate secrets between children and parents.

• Teach children how to say no, ask for help, and control who touches them and how.

• Model self-protective and limit-setting behavior for children.

Should it ever become necessary to help a child recover from a sexual assault:

• Listen carefully to understand the child.

• Support the child for telling through praise, belief, sympathy, and lack of blame.

• Know local resources and choose help carefully.

• Provide opportunities to talk about the assault.

• Provide opportunities for the entire family to go through a recovery process.

Sexual assault affects everyone. To help deal with this social problem:

• Provide care and support to those who have been victimized.

• Recognize that offenders may not change behavior even with intervention.

• Organize neighborhood programs to support each other’s efforts to protect children.

• Encourage schools to provide information about sexual assault as a problem of health and safety.

• Organize community groups to support educational treatment and law enforcement programs.

Modified from Adams C, Fay J: No more secrets: protecting your child from sexual assault, San Luis Obispo, Calif, 1981, Impact.

image NURSING CARE PLAN

The Child Who Is Maltreated

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Key Points

• Common infectious disorders during early childhood include communicable diseases, intestinal parasitic infections, conjunctivitis, and stomatitis.

• Nursing goals in the treatment of a communicable disease are identification, prevention of transmission, provision of comfort, and prevention of complications.

• Intestinal parasitic diseases constitute the most common infections in the world; giardiasis and enterobiasis are the most widespread parasitic infections among children in the United States.

• Although the incidence of poisoning has decreased in the past 30 years as a result of more stringent packaging regulations, childhood poisoning remains a serious health concern.

• The major principles of treatment for poisoning include assessment and the ABCs of resuscitation (airway, breathing, and circulation), minimization of poison absorption, prevention of complications, family support, and prevention of recurrence.

• Communication with the area PCC is essential in the treatment of any poisoning.

• Acetaminophen poisoning is the most common accidental drug poisoning among children and occurs primarily from acute overdose.

• The most important factor contributing to lead poisoning is its availability in the child’s environment. Lead-based paint is the most toxic source of lead.

• Because of increasing awareness of the detrimental effects of low levels of lead on the developing nervous system, acceptable BLLs have been decreasing and now are at less than 10 mcg/dl.

• Child maltreatment may take the form of physical abuse or neglect, emotional abuse or neglect, or sexual abuse.

• Parental, child, and environmental characteristics are criteria that may predispose children to maltreatment.

• Identification of abuse entails securing evidence of maltreatment, taking a history pertaining to the incident, and assessing parental and child behaviors.

• The reported incidence of sexual abuse has increased in the past decade; common forms are incest, molestation, rape, exhibitionism, child pornography, child prostitution, and pedophilia.

Answers to Critical Thinking Exercise

Poisoning

1. Yes, there is sufficient evidence to formulate an answer for Mrs. Berry.

2. a. When a child ingests a poisonous substance, the initial goal is to limit the absorption of the poison in the gastrointestinal system and enhance elimination. Specific actions that are taken to limit absorption and enhance elimination of poisons are to administer an agent that neutralizes the poison such as activated charcoal. Multiple administrations of activated charcoal may also enhance excretion of the poison through the gastrointestinal tract, thus limiting absorption.

b. Ipecac is an emetic that induces vomiting by producing an irritant effect on the gastric mucosa. In the past, ipecac was recommended for home treatment of some cases of ingestion. However, ipecac is no longer recommended for routine home treatment of poisoning.

c. Ipecac induces emesis, which may predispose the child to aspiration if level of consciousness is affected. In addition, emesis may be prolonged beyond the desired time when oral hydration is desirable. In the event that hydrocarbons or corrosive substances are ingested, inducing vomiting with ipecac may cause esophageal damage and aspiration into the lungs.

3. The first priority for nursing care is to advise Mrs. Berry to call the poison control center immediately to obtain guidance. Each ingestion is treated individually, and information from the poison control center is essential to determine the most appropriate action. The most toxic ingredient in a chewable multivitamin is iron, which produces symptoms after several hours. Therefore treatment, if needed, should begin long before symptoms appear.

4. Yes, there is sufficient information to formulate an answer for Mrs. Berry.

References

American Academy of Pediatrics, Committee on Infectious Diseases. Red book: 2009 report of the Committee on Infectious Diseases. In Pickering L, ed.: Red book: 2009 report of the Committee on Infectious Diseases, ed 28, Elk Grove Village, Ill: The Academy, 2009.

American Academy of Pediatrics, Committee on Environmental Health. Lead exposure in children: prevention, detection, and management. Pediatrics. 2005;116(4):1036–1046.

American Academy of Pediatrics, Committee on Child Abuse and Neglect. Shaken baby syndrome: rotational cranial injuries (technical report). Pediatrics. 2001;108(1):206–210.

Bronstein, AC, Spyker, DA, Cantilena, LR, Jr., et al. 2007 Annual report of the American Association of Poison Control Centers’ National Poison Data System (NPDS): 25th annual report. Clin Toxicol (Phila). 2008;46(10):927–1057.

Calam, R, Horne, L, Glasgow, D, et al. Psychological disturbances and child sexual abuse: a follow-up study. Child Abuse Negl. 1998;22(9):901–913.

Carbaugh, SF. The long road home: understanding shaken baby syndrome. Adv Neonatal Care. 2004;4:105–117.

Castiglia, R. Shaken baby syndrome. J Pediatr Health Care. 2001;15(2):78–80.

Centers for Disease Control and Prevention. Deaths associated with hypocalcemia from chelation therapy—Texas, Pennsylvania, and Oregon, 2003-2005. MMWR. 2006;55(08):204–207.

Centers for Disease Control and Prevention. Statewide plan for childhood blood lead screening. Atlanta: The Centers; 2005.

Centers for Disease Control and Prevention. Managing elevated blood lead levels among young children: recommendations from the Advisory Committee on Childhood Lead Poisoning Prevention. Atlanta: The Centers; 2002.

Cheng, A, Ratnapalan, S. Improving the palatability of activated charcoal in pediatric patients. Pediatr Emerg Care. 2007;23(6):384–386.

Chiesa, A, Duhaime, A. Abusive head trauma. Pediatr Clin North Am. 2009;56(2):317–331.

Christian, CW, Lavelle, JM, DeJong, AR, et al. Forensic evidence findings in prepubertal victims of sexual assault. Pediatrics. 2000;106:100–104.

Christian, CW, Rubin, DM. Sexual abuse. In: Giardino AP, Giardino ER, eds. Recognition of child abuse for the mandated reporter. St Louis: GW Medical Publishing, 2002.

Clifton, JC. Mercury exposure and public health. Pediatr Clin North Am. 2007;54(2):237–269.

Criddle, LM. An overview of pediatric poisonings. AACN Adv Crit Care. 2007;18(2):109–118.

Cyr, M, Wright, J, McDuff, P, et al. Intrafamilial sexual abuse: brother-sister incest does not differ from father-daughter incest and stepfather-stepdaughter incest. Child Abuse Negl. 2002;26(9):957–973.

Dessypris, N, Dikalioti, SK, Skalkidis, I, et al. Combating unintentional injury in the United States: lessons learned from the ICD-10 classification period. J Trauma. 2009;66(2):519–525.

Donelan-McCall, N, Eckenrode, J, Olds, D. Home visiting for the prevention of child maltreatment: lessons learned during the past 20 years. Pediatr Clin North Am. 2009;56(2):389–403.

Eckenrode, J, Ganzel, B, Henderson, C, et al. Preventing child abuse and neglect with a program of nurse home visitation: the limiting effects of domestic violence. JAMA. 2000;284(11):1385–1391.

Eisenstein, L, Bodager, D, Ginzl, D. Outbreak of giardiasis and cryptosporidiosis associated with a neighborhood interactive water fountain—Florida. 2006, J Environ Health. 2008;71(3):18–22.

Eldridge, DL, Van Eyk, J, Kornegay, C. Pediatric toxicology. Emerg Med Clin North Am. 2007;25(2):283–308.

Erickson, L, Thompson, T. A review of a preventable poison: pediatric lead poisoning. J Soc Pediatr Nurs. 2005;10(4):171–182.

Ewing-Cobb, L, Kramer, L, Prasad, M, et al. Neuroimaging, physical, and developmental findings after inflicted and noninflicted traumatic brain injury in young children. Pediatrics. 1998;102:300–307.

Finkel, MA, DeJong, AR. Medical findings in child sexual abuse. In: Reece RM, Ludwig S, eds. Child abuse medical diagnosis and management. Philadelphia: Lippincott Williams & Wilkins, 2001.

Franklin, RL, Rodgers, GB. Unintentional child poisonings treated in United States hospital emergency departments: national estimates of incident cases, population-based poisoning rates, and product involvement. Pediatrics. 2008;122(6):1244–1251.

Frazer, L. Soil in the city: a prime source of lead. Environ Health Perspect. 2008;116(12):A522.

Fuloria, M, Kreiter, S. The newborn examination, part I, Emergencies and common abnormalities involving the skin, head, neck, chest, and respiratory and cardiovascular systems. Am Fam Physician. 2002;65(1):61–68.

Galea, SA, Sweet, A, Beninger, P, et al. The safety profile of varicella vaccine: a 10-year review. J Infect Dis. 2008;197(Suppl 2):S165–S169.

Gara, MA, Allen, LA, Herzog, EP, et al. The abused child as parent: the structure and content of physically abused mothers’ perceptions of their babies. Child Abuse Negl. 2000;24(5):627–639.

Giardino ER, Giardino AP, eds. Nursing approach to the evaluation of child maltreatment. St Louis: GW Medical Publishing, 2003.

Goldman, J, Salus, MK, Wolcott, D, et al, What factors contribute to child abuse and neglect?. A coordinated response to child abuse and neglect: the foundation for practice 2003. Child Welfare Information Gateway, available at www.childwelfare.gov/pubs/usermanuals/foundation/foundatione.cfm [(accessed June 4, 2007)].

Greene, S, Harris, C, Singer, J. Gastrointestinal decontamination of the poisoned patient. Pediatr Emerg Care. 2008;24(3):176–189.

Heavey, E. Lead poisoning in children: still a threat. Nursing. 2008;38(12):17–18.

Hornor, G. Repeated sexual abuse allegations: a problem for primary care providers. J Pediatr Health Care. 2001;15(2):71–76.

Johnson, CF. Child sexual abuse. Lancet. 2004;364(9432):462–470.

Kaczor, K, Pierce, MC, Makoroff, K, et al. Bruising and physical child abuse. Clin Pediatr Emerg Med. 2006;7(3):153–160.

Kendrick D, Barlow J, Hampshire A, et al: Parenting interventions for the prevention of unintentional injuries in childhood, Cochrane Database Syst Rev Oct 17(4):CD006020, 2007.

Kendrick D, Coupland C, Mulvaney C, et al: Home safety education and provision of safety equipment for injury prevention, Cochrane Database Syst Rev Jan 24(1):CD005014, 2007.

Kendrick, D, Smith, S, Sutton, A, et al. Effect of education and safety equipment on poisoning-prevention practices and poisoning: systematic review, meta-analysis and meta-regression. Arch Dis Child. 2008;93(7):599–608.

Lederman, C, Lederman, M. Ophthalmologic emergencies. In Crain EF, Gershel JC, eds.: Clinical manual of emergency pediatrics, ed 4, New York: McGraw-Hill, 2003.

Leider, HS, Irving, SY, Mauricio, R, et al. Munchausen syndrome by proxy: a case report. AACN Clin Issues. 2005;16(2):178–184.

Leung, AK, Robson, WL, Leong, AG. Herpes zoster in childhood. J Pediatr Health Care. 2006;20(5):1783–1785.

Levin, A. Retinal hemorrhages: advances in understanding. Pediatr Clin North Am. 2009;56(2):333–344.

Levin, R, Brown, MJ, Kashtock, ME, et al, Lead exposures in U.S. children, 2008: implications for prevention. Environ Health Perspect 2008;116(10):1285–1293. available at www.ncbi.nlm.nih.gov/pmc/articles/PMC2569084/?tool=pubmed [(accessed February 1, 2010)].

Lichtenstein, SJ, Rinehart, M. Levofloxacin Bacterial Conjunctivitis Study Group: Efficacy and safety of 0.5% levofloxacin ophthalmic solution for the treatment of bacterial conjunctivitis in pediatric patients. J AAPOS. 2003;7(5):317–324.

Lidsky, TI, Schneider, JS. Adverse effects of childhood lead poisoning: the clinical neuropsychological perspective. Environ Res. 2006;100(1):284–293.

Madden, MA. Responding to pediatric poisoning. Nursing. 2008;38(8):52–55.

McClain, N, Giardet, R, Lahoti, S, et al. Evaluation of sexual abuse in the pediatric patient. J Pediatr Health Care. 2000;14(3):93–102.

McMillian, H. Child maltreatment: what we know in the year 2000. Can J Psychiatry. 2000;45(8):702–709.

Mekonnen, R, Noonan, K, Rubin, D. Achieving better healthcare outcomes for children in foster care. Pediatr Clin North Am. 2009;56(2):405–415.

Miehl, NJ. Shaken baby syndrome. J Forensic Nurs. 2005;1(3):111–117.

Nasser M, Fedorowicz Z, Khoshnevisan MH, et al: Acyclovir for treating primary herpetic gingivostomatitis, Cochrane Database Syst Rev Oct 8(4): CD006700, 2008.

National Center on Shaken Baby Syndrome. All about SBS/AHT. n.d., available at www.dontshake.org/sbs.php?topNavID=2&subNavID=10. [(accessed May 29, 2009)].

Nelms, BC. Emotional abuse: helping prevent the problem. J Pediatr Health Care. 2001;15(3):103–104.

Phillips, B. Towards evidence-based medicine for paediatricians. Arch Dis Child Educ Pract Ed. 2008;93(4):129.

Putnam, FW. Ten year update review: child sexual abuse. J Am Acad Child Adolesc Psychiatry. 2003;42(3):269–278.

Rose, PW, Harnden, A, Brueggemann, AB, et al. Chloramphenicol treatment for acute infective conjunctivitis in children in primary care: a randomized double-blind placebo-controlled trial. Lancet. 2005;366(9479):37–43.

Sheffield, P, Serwint, JR. Emetics, cathartics, and gastric lavage. Pediatr Rev. 2008;29(6):214–215.

Shields, JM, Gleim, ER, Beach, MJ. Prevalence of Cryptosporidium spp. and Giardia intestinalis in swimming pools, Atlanta, Georgia. Emerg Infect Dis. 2008;14(6):948–950.

US Department of Health and Human Services, Administration on Children, Youth and Families. Child maltreatment 2007. Washington, DC: US Government Printing Office; 2009.

Walls, C. Shaken baby syndrome education: a role for nurse practitioners working with families of small children. J Pediatr Health Care. 2006;20(5):304–310.

Wells, K. Substance abuse and child maltreatment. Pediatr Clin North Am. 2009;56(2):354–362.

Wood, N, McIntyre, P. Pertussis: review of epidemiology, diagnosis, management and prevention. Paediatr Respir Rev. 2008;9(3):201–212.

Woolf, AD, Goldman, R, Bellinger, DC. Update on clinical management of childhood lead poisoning. Pediatr Clin North Am. 2007;54(2):271–294.

Yoder, JS, Beach, MJ. Centers for Disease Control and Prevention (CDC): Giardiasis surveillance—United States, 2003-2005. MMWR Surveill Summ. 2007;56(7):11–18.


*Educational materials may be obtained from the National Shingles Foundation, 590 Madison Ave., 21st Floor, New York, NY 10022; 212-222-3390; www.vzvfoundation.org.

*The most common substances in each category are in parentheses. Substances ingested are not necessarily the most toxic but often are readily available.

Also available by calling 800-222-1222 or online at American Association of Poison Control Centers, www.aapcc.org.

*Additional information is available from the Children’s Bureau, Administration for Children and Families, 370 L’Enfant Promenade SW, Washington, DC 20447; 800-422-4453; www.acf.hhs.gov/programs/cb.

*Telephone numbers are usually listed under “Child Abuse” in the business white pages of the local directory, or call the emergency child abuse hotline: 800-422-4453 (800-4-A-CHILD).

*675 W. Foothill Blvd., Suite 220, Claremont, CA 91711; 909-621-6184; www.parentsanonymous.org.

Sources of information are Prevent Child Abuse America, 228 S. Wabash Ave., 10th Floor, Chicago, IL 60604; 312-663-3520 or 800-Children; www.preventchildabuse.org; and American Humane, 63 Inverness Drive East, Englewood, CO 80112; 800-227-4645 (outside Colorado) or 303-792-9900; www.americanhumane.org.